1,4-Naphthalenedione,2-bromo-
1,4-Naphthalenedione,2-bromo- structure
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Common Name | 1,4-Naphthalenedione,2-bromo- | ||
|---|---|---|---|---|
| CAS Number | 2065-37-4 | Molecular Weight | 237.04900 | |
| Density | 1.757g/cm3 | Boiling Point | 324.2ºC at 760mmHg | |
| Molecular Formula | C10H5BrO2 | Melting Point | 131-133ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 124.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition.
Eur. J. Med. Chem. 63 , 523-30, (2013) Continuing our screening program for novel anti-parasite compounds, we synthesized seven 1,4-naphthoquinones coupled to 1,2,3-triazoles, five nor-β-lapachone-based 1,2,3-triazoles and ten α-lapachone-based 1,2,3-triazoles. These and other naphthoquinonoid com... |
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2-Bromo-1,4-naphthoquinone: a potentially improved substitute of menadione in Apatone™ therapy.
Braz. J. Med. Biol. Res. 45(8) , 701-10, (2012) Apatone™, a combination of menadione (2-methyl-1,4-naphthoquinone, VK3) and ascorbic acid (vitamin C, VC) is a new strategy for cancer treatment. Part of its effect on tumor cells is related to the cellular pro-oxidative imbalance provoked by the generation o... |
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Expedient, one-pot preparation of fused indoles via CAN-catalyzed three-component domino sequences and their transformation into polyheterocyclic compounds containing pyrrolo[1,2-a]azepine fragments.
Org. Biomol. Chem. 8(15) , 3426-36, (2010) The CAN-catalyzed three-component between reaction between primary amines, beta-dicarbonyl compounds and naphthoquinones or 2-bromonaphthoquinones afforded, respectively, 5-hydroxybenzo[g]indoles and benzo[f]indole-4,9-diones, the former of which were transfo... |
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Reaction of Some Indoles with 1,4-Naphthoquinones in the Presence of Pd(OAc)2. Tanoue Y, et al.
J. Heterocycl. Chem. 51(S1) , E364, (2014)
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Stereoselective synthesis of deoxy analogues of the 3C-protease inhibitor thysanone. Brimble MA and Elliott RJR
Tetrahedron 58(1) , 183-189, (2002)
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The Photochemical Reaction of 1,4-Naphthoquinone Derivatives with Hydrogen Donors. Maruyama K and Arakawa S.
Bull. Chem. Soc. Jpn. 47(8) , 1960-1966, (1974)
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