Genapol O
Genapol O structure
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Common Name | Genapol O | ||
|---|---|---|---|---|
| CAS Number | 9004-98-2 | Molecular Weight | 312.53000 | |
| Density | 1.07g/cm3 | Boiling Point | 100ºC | |
| Molecular Formula | C20H40O2 | Melting Point | 30ºC | |
| MSDS | Chinese USA | Flash Point | >230 °F | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Antimicrobial Nanoemulsion Formulation with Improved Penetration of Foliar Spray through Citrus Leaf Cuticles to Control Citrus Huanglongbing.
PLoS ONE 10 , e0133826, (2015) Huanglongbing (HLB) is the most serious disease affecting the citrus industry worldwide to date. The causal agent, Candidatus Liberibacter asiaticus (Las), resides in citrus phloem, which makes it difficult to effectively treat with chemical compounds. In thi... |
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TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite.
J. Immunol. 181(5) , 3464-73, (2008) TLR adaptor MyD88 activation is important in host resistance to Toxoplasma gondii during i.p. infection, but the function of this signaling pathway during oral infection, in which mucosal immunity assumes a predominant role, has not been examined. In this stu... |
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Key structure of brij for overcoming multidrug resistance in cancer.
Biomacromolecules 14(2) , 424-30, (2013) Multidrug resistance (MDR) is a major barrier to the chemotherapy treatment of many cancers. However, some nonionic surfactants, for example, Brij, have been shown to restore the sensitivity of MDR cells to such drugs. The aim of this study was to explore the... |
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Solubilisation capacity of Brij surfactants.
Int. J. Pharm. 436(1-2) , 631-5, (2012) The aim of this study was to investigate the potential of selected Brij non-ionic surfactants for enhancing the solubility of poorly water-soluble drugs. Griseofulvin was selected as a model drug candidate enabling comparisons to be made with the solubilisati... |
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Enhanced percutaneous permeability of diclofenac using a new U-type dilutable microemulsion.
Drug Dev. Ind. Pharm. 34(4) , 403-12, (2008) Enhanced systemic absorption in vivo and percutaneous penetration in vitro was demonstrated after transdermal administration of diclofenac sodium formulated in U-type microemulsion. Diclofenac sodium was solubilized in a typical four-component system consisti... |
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Cytochrome P450 system proteins reside in different regions of the endoplasmic reticulum.
Biochem. J. 464(2) , 241-9, (2014) Cytochrome P450 (P450) function is dependent on the ability of these enzymes to successfully interact with their redox partners, NADPH-cytochrome P450 reductase (CPR) and cytochrome b5, in the endoplasmic reticulum (ER). Because the ER is heterogeneous in lip... |
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Idebenone-loaded solid lipid nanoparticles for drug delivery to the skin: in vitro evaluation.
Int. J. Pharm. 434(1-2) , 169-74, (2012) Idebenone (IDE), a synthetic derivative of ubiquinone, shows a potent antioxidant activity that could be beneficial in the treatment of skin oxidative damages. In this work, the feasibility of targeting IDE into the upper layers of the skin by topical applica... |
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Quality by design: characterization of self-nano-emulsified drug delivery systems (SNEDDs) using ultrasonic resonator technology.
Int. J. Pharm. 341(1-2) , 189-94, (2007) In the present work, a novel application of ultrasonic measurements is detailed to characterize nano-emulsion formulations as a part of the overall Quality by Design (QbD) goal. Ultrasonic resonator technology (URT) was utilized to measure sound velocity and ... |
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In situ gelling hexagonal phases for sustained release of an anti-addiction drug.
Colloids Surf. B Biointerfaces 87(2) , 391-8, (2011) In this study, fluid precursor formulations for subcutaneous injection and in situ formation of hexagonal phase gels upon water absorption were developed as a strategy to sustain the release of naltrexone, a drug used for treatment of drug addiction. Precurso... |
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Synaptic proteins associate with a sub-set of lipid rafts when isolated from nerve endings at physiological temperature.
Biochem. Biophys. Res. Commun. 348(4) , 1334-42, (2006) Although the high presence of cholesterol in nerve terminals is well documented, specific roles of this lipid in transmitter release have remained elusive. Since cholesterol is a highly enriched component in the membrane microdomains known as lipid rafts, it ... |