(E)-3-(4-Methoxyphenyl)acrylic acid
(E)-3-(4-Methoxyphenyl)acrylic acid structure
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Common Name | (E)-3-(4-Methoxyphenyl)acrylic acid | ||
|---|---|---|---|---|
| CAS Number | 943-89-5 | Molecular Weight | 178.185 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 342.6±17.0 °C at 760 mmHg | |
| Molecular Formula | C10H10O3 | Melting Point | 173.5ºC | |
| MSDS | Chinese USA | Flash Point | 138.6±14.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Antimicrobial activity of natural products from the flora of Northern Ontario, Canada.
Pharm. Biol. 53(6) , 800-6, (2015) The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only a few antimicrobial agents left that can be used against MD... |
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A practical procedure for the large-scale preparation of methyl (2R,3S)-3-(4-methoxyphenyl)glycidate, a key intermediate for diltiazem.
J. Org. Chem. 67(13) , 4599-601, (2002) A practical synthesis of methyl (2R,3S)-3-(4-methoxyphenyl)glycidate (-)-2, a key intermediate for diltiazem (1), was developed. Treatment of methyl (E)-4-methoxycinnamate 3 with chiral dioxirane, generated from chiral ketone 4, provided (-)-2 in 77% ee and 8... |
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Enzymatic synthesis of cinnamic acid derivatives.
Biotechnol. Lett. 28(8) , 581-5, (2006) Using Novozym 435 as catalyst, the syntheses of ethyl ferulate (EF) from ferulic acid (4-hydroxy 3-methoxy cinnamic acid) and ethanol, and octyl methoxycinnamate (OMC) from p-methoxycinnamic acid and 2-ethyl hexanol were successfully carried out in this study... |
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The modulatory influence of p-methoxycinnamic acid, an active rice bran phenolic acid, against 1,2-dimethylhydrazine-induced lipid peroxidation, antioxidant status and aberrant crypt foci in rat colon carcinogenesis.
Chem. Biol. Interact. 196(1-2) , 11-22, (2012) We investigated the chemopreventive effect of p-methoxycinnamic acid (p-MCA), an active phenolic acid of rice bran, turmeric, and Kaemperfia galanga against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Male albino Wistar rats were randomly divided ... |
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Induction of histone acetylation and growth regulation in eryrthroleukemia cells by 4-phenylbutyrate and structural analogs.
Anticancer Res. 19(3A) , 1971-6, (1999) The objective of this investigation was to study the relationship between histone acetylation and growth inhibition by 4-phenylbutyrate and structural analogs. Inhibition of growth of DS19 mouse erythroleukemia cells and K562 human leukemic cells by 4-phenylb... |
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Oligosaccharide microscale analysis by circular dichroic spectroscopy: reference spectra for chromophoric D-fructofuranoside derivatives.
Carbohydr. Res. 239 , 11-33, (1993) The microscale analytical method that is being developed in this group for the structure determination of oligosaccharides yields monosaccharide derivatives bearing two types of chromophores suitable for exciton-coupling, namely, 4-bromobenzoate (lambda max 2... |
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Insulin-secretagogue activity of p-methoxycinnamic acid in rats, perfused rat pancreas and pancreatic beta-cell line.
Basic Clin Pharmacol Toxicol. 102(5) , 476-82, (2008) This study investigated the effect of p-methoxycinnamic acid (p-MCA) on plasma glucose and insulin concentrations in normal and streptozotocin-induced diabetic rats. In both fasting and glucose-loading conditions, an oral administration of p-MCA (40-100 mg/kg... |
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Mechanisms of p-methoxycinnamic acid-induced increase in insulin secretion.
Horm. Metab. Res. 43(11) , 766-73, (2011) p-Methoxycinnamic acid (p-MCA) is a cinnamic acid derivative that shows various pharmacologic actions such as hepatoprotective and antihyperglycemic activities. The present study was to elucidate the mechanisms by which p-MCA increases [Ca²⁺]i and insulin sec... |
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Natural products modulate Shigella-host-cell interaction.
J. Med. Microbiol. 60(Pt 11) , 1626-32, (2011) This study focused on identifying possible new options derived from natural sources for the treatment of bacterial infections. Several natural products were investigated for their potential in modulating Shigella-host-cell interactions. The proliferation of S... |
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Cinnamic acid and its derivatives inhibit fructose-mediated protein glycation.
Int. J. Mol. Sci. 13 , 1778-89, (2012) Cinnamic acid and its derivatives have shown a variety of pharmacologic properties. However, little is known about the antiglycation properties of cinnamic acid and its derivatives. The present study sought to characterize the protein glycation inhibitory act... |