H-Tyr-NH2

H-Tyr-NH2 Structure
H-Tyr-NH2 structure
Common Name H-Tyr-NH2
CAS Number 4985-46-0 Molecular Weight 216.665
Density 1.268g/cm3 Boiling Point 437.7ºC at 760mmHg
Molecular Formula C9H13ClN2O2 Melting Point 153.5°C
MSDS Chinese USA Flash Point 218.5ºC

Solvent selection and optimization of α-chymotrypsin-catalyzed synthesis of N-Ac-Phe-Tyr-NH2 using mixture design and response surface methodology.

Biotechnol. Prog. 28(6) , 1443-9, (2012)

A peptide, N-Ac-Phe-Tyr-NH(2) , with angiotensin I-converting enzyme (ACE) inhibitor activity was synthesized by an α-chymotrypsin-catalyzed condensation reaction of N-acetyl phenylalanine ethyl ester (N-Ac-Phe-OEt) and tyrosinamide (Tyr-NH(2) ). Three kinds ...

Enzymatic copolymerization alters the structure of unpolymerized mixtures of the biomimetic monomers: the amphiphilic decyl ester of L-tyrosine and L-tyrosineamide--an AFM investigation of nano- to micrometer-scale structure differences.

Biomacromolecules 5(5) , 1869-76, (2004)

Previously, we have shown that the amphiphilic decyl esters of both D- and L-tyrosine (DELT) self-assemble in aqueous solution above their critical micelle concentration values to form long rodlike structures that can be enzymatically polymerized. In the curr...

Derivatization and purification of bisecting tyrosinamide-oligosaccharides from ovotransferrin.

Arch. Biochem. Biophys. 315(2) , 460-6, (1994)

The major N-linked oligosaccharides from ovotransferrin were purified on a large scale. The oligosaccharides were released from 5 g of the glycoprotein using N-glycosidase F and isolated from a mixed bed ion exchange column. Reducing-oligosaccharides were rea...

Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines.

Steroids 77(5) , 403-12, (2012)

L-para-Tyrosine was linked to ortho-hydroxyaniline, meta-hydroxyaniline and para-hydroxyaniline giving three distinct tyrosinamide molecules. The new extended amino acid derivatives were constructed to imitate, in part, the estradiol (E(2), the natural female...

Probing the binding specificity of C-type lectins in vivo.

Meth. Enzymol. 363 , 90-104, (2003)

Synthesis, spectroscopic and structural elucidation of tyrosinamide hydrogensquarate monohydrate.

Amino Acids 36(2) , 195-201, (2009)

Synthesis, isolation, spectroscopic and structural elucidation of tyrosinamide hydrogensquarate monohydrate (I) is reported on the basis of quantum chemical DFT calculations, vibrational analysis and experimental linear-polarized IR-spectroscopy in solid stat...

Preparative purification of a high-mannose type N-glycan from soy bean agglutinin by hydrazinolysis and tyrosinamide derivatization.

Anal. Biochem. 265(2) , 313-6, (1998)

The N-linked oligosaccharide from soy bean agglutinin (Man9) was isolated on a preparative scale following derivatization with Boc-tyrosine. The procedure utilized preparative hydrazinolysis to release the oligosaccharide and yielded multi-micromol quantities...

Reversal of tyrosinamide-oligosaccharide derivatization by Edman degradation.

Anal. Biochem. 222(1) , 243-50, (1994)

In a previous report (Tamura, T., Wadhwa, M.S., and Rice, K.G. (1994) Anal. Biochem. 216, 335-344) we described the derivatization of N-linked oligosaccharides with Boc-tyrosine resulting in the formation of tyrosinamide-oligosaccharides. Attachment of Boc-ty...

A novel approach to 14C label N-linked oligosaccharides.

Anal. Biochem. 247(2) , 448-50, (1997)

In vivo targeting function of N-linked oligosaccharides. Pharmacokinetic and biodistribution of N-linked oligosaccharides.

Adv. Exp. Med. Biol. 376 , 271-82, (1995)