1-(BROMOMETHYL)-4,5-DIMETHOXY-2-NITROBENZENE

1-(BROMOMETHYL)-4,5-DIMETHOXY-2-NITROBENZENE Structure
1-(BROMOMETHYL)-4,5-DIMETHOXY-2-NITROBENZENE structure
Common Name 1-(BROMOMETHYL)-4,5-DIMETHOXY-2-NITROBENZENE
CAS Number 53413-67-5 Molecular Weight 276.08400
Density 1.544g/cm3 Boiling Point 372.3ºC at 760mmHg
Molecular Formula C9H10BrNO4 Melting Point 131-133ºC(lit.)
MSDS Chinese USA Flash Point 179ºC
Symbol GHS05
GHS05
Signal Word Danger

Caged vanilloid ligands for activation of TRPV1 receptors by 1- and 2-photon excitation.

Biochemistry 45(15) , 4915-26, (2006)

Nociceptive neurons in the peripheral nervous system detect noxious stimuli and report the information to the central nervous system. Most nociceptive neurons express the vanilloid receptor, TRPV1, a nonselective cation channel gated by vanilloid ligands such...

Bright building blocks for chemical biology.

ACS Chem. Biol. 9(4) , 855-66, (2014)

Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology. As we noted in a previous review (Lavis, L. D.; Raines, R. T. ACS Chem. Biol. 2008, 3, 142-155), the extant collection of fluorescent probes is built on a modest set o...

Spatially discrete, light-driven protein expression.

Chem. Biol. 9(12) , 1347-53, (2002)

Transgene-based inducible expression systems offer the potential to study the influence of any gene at any point during an organism's lifetime. However, the expression of individual genes is both temporally and spatially (i.e., cell/tissue)-regulated. The ind...

Model compounds of caged capsaicin: design, synthesis, and photoreactivity.

J. Org. Chem. 68(23) , 9100-4, (2003)

Molecules were prepared with substituted nitrobenzyl groups covalently bonded to N-(4-hydroxy-3-methoxybenzyl)acetamide (2) by ether or carbonate linkages. These compounds decomposed under irradiation at 363 nm. Those with carbonate linkages decomposed at slo...

Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand.

Chem. Commun. (Camb.) 49(76) , 8453-5, (2013)

The use of a caged G-quadruplex ligand allows for transcriptional control of quadruplex-containing genes using UV light as an external trigger. An important oncogene, SRC, involved in the initiation and proliferation of epithelial tumours is shown to be signi...

Caged AG10: new tools for spatially predefined mitochondrial uncoupling.

Mol. Biosyst. 5(5) , 450-7, (2009)

The study of mitochondria and mitochondrial Ca2+ signalling in localised regions is hampered by the lack of tools that can uncouple the mitochondrial membrane potential (DeltaPsi(m)) in a spatially predefined manner. Although there are a number of existing mi...

Light-directed generation of the actin-activated ATPase activity of caged heavy meromyosin.

Biochemistry 35(10) , 3170-4, (1996)

An understanding of the molecular mechanism of muscle contraction will require a complete description of the kinetics of the myosin motor in vitro and in vivo. To this end chemical relaxation studies employing light-directed generation of ATP from caged ATP h...

Surface functionalization of PEEK films using photochemical routes. Henneuse-Boxus C, et al.

Eur. Polymer J. 37(1) , 9-18, (2001)

Synthesis and Characterizations of Positive-Working Photosensitive Polyimides Having 4, 5-Dimethoxy-o-Nitrobenzyl Side Group. Ryu S, et al.

Bull. Korean Chem. Soc. 29(9) , 1689, (2008)

Light-triggered strand exchange reaction using the change in the hydrogen bonding pattern of a nucleobase analogue. Morihiro K, et al.

Chem. Sci. 5(2) , 744-750, (2014)