2-bromohexadecanoic acid
2-bromohexadecanoic acid structure
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Common Name | 2-bromohexadecanoic acid | ||
|---|---|---|---|---|
| CAS Number | 18263-25-7 | Molecular Weight | 335.32 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 403.4±18.0 °C at 760 mmHg | |
| Molecular Formula | C16H31BrO2 | Melting Point | 52-54 °C | |
| MSDS | Chinese USA | Flash Point | 197.8±21.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Local palmitoylation cycles define activity-regulated postsynaptic subdomains.
J. Cell Biol. 202(1) , 145-61, (2013) Distinct PSD-95 clusters are primary landmarks of postsynaptic densities (PSDs), which are specialized membrane regions for synapses. However, the mechanism that defines the locations of PSD-95 clusters and whether or how they are reorganized inside individua... |
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Estrogen receptor-alpha 36 mediates the anti-apoptotic effect of estradiol in triple negative breast cancer cells via a membrane-associated mechanism.
Biochim. Biophys. Acta 1843(11) , 2796-806, (2014) 17β-Estradiol can promote the growth and development of several estrogen receptor (ER)-negative breast cancers. The effects are rapid and non-genomic, suggesting that a membrane-associated ER is involved. ERα36 has been shown to mediate rapid, non-genomic, me... |
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Identification of G protein alpha subunit-palmitoylating enzyme.
Mol. Cell. Biol. 29(2) , 435-47, (2009) The heterotrimeric G protein alpha subunit (Galpha) is targeted to the cytoplasmic face of the plasma membrane through reversible lipid palmitoylation and relays signals from G-protein-coupled receptors (GPCRs) to its effectors. By screening 23 DHHC motif (As... |
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Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella).
Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 155(2) , 381-8, (2012) The peroxisome proliferator-activated receptors (PPARs) are ligand-dependent transcription factors belonging to the nuclear receptor family, and can regulate various genes involved in lipid metabolism. The aim of the present study was to investigate the tissu... |
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Freely turning over palmitate in erythrocyte membrane proteins is not responsible for the anchoring of lipid rafts to the spectrin skeleton: a study with bio-orthogonal chemical probes.
Biochim. Biophys. Acta 1828(3) , 924-31, (2013) Erythrocyte lipid rafts are anchored to the underlying spectrin membrane skeleton [A. Ciana, C. Achilli, C. Balduini, G. Minetti, On the association of lipid rafts to the spectrin skeleton in human erythrocytes, Biochim. Biophys. Acta 1808 (2011) 183-190]. Th... |
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Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.
PLoS Biol. 12(7) , e1001908, (2014) Postsynaptic scaffolding proteins regulate coordinated neurotransmission by anchoring and clustering receptors and adhesion molecules. Gephyrin is the major instructive molecule at inhibitory synapses, where it clusters glycine as well as major subsets of GAB... |
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Plasma membrane localization is required for RasA-mediated polarized morphogenesis and virulence of Aspergillus fumigatus.
Eukaryotic Cell 11(8) , 966-77, (2012) Ras is a highly conserved GTPase protein that is essential for proper polarized morphogenesis of filamentous fungi. Localization of Ras proteins to the plasma membrane and endomembranes through posttranslational addition of farnesyl and palmitoyl residues is ... |
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Protein palmitoylation inhibition by 2-bromopalmitate alters gliding, host cell invasion and parasite morphology inToxoplasma gondii
Mol. Biochem. Parasitol. 184(1) , 39-43, (2012) Graphical abstract |
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Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells.
Am. J. Physiol. Gastrointest. Liver Physiol. 294(5) , G1181-90, (2008) We have shown earlier that platelet-activating factor (PAF) causes apoptosis in enterocytes via a mechanism that involves Bax translocation to mitochondria, followed by caspase activation and DNA fragmentation. Herein we report that, in rat small intestinal e... |
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Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation.
J. Biol. Chem. 286(7) , 5175-86, (2011) Palmitoylation is a lipid modification that confers diverse functions to target proteins and is a contributing factor for many neuronal diseases. In this study, we demonstrate using [(3)H]palmitic acid labeling and acyl-biotinyl exchange that native and expre... |