- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 2-bromohexadecanoic acid
- Price: ￥258.0/10g ￥1018.0/50g
- Purity: 95.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: 2-bromo-Hexadecanoic acid
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-Bromohexadecanoic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
18263-25-7
18263-25-7 structure
- Name: 2-bromohexadecanoic acid
- Chemical Name: 2-bromohexadecanoic acid
- CAS Number: 18263-25-7
- Molecular Formula: C16H31BrO2
- Molecular Weight: 335.32
- Catalog: Chemical reagent Organic reagent fatty acid
- Create Date: 2018-03-07 08:00:00
- Modify Date: 2024-01-02 17:32:34
-
2-Bromohexadecanoic acid (2-Bromopalmitic acid) can be converted to 2-bromopalmitate (2-BP). 2-BP is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-BP inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis[1].
| Name | 2-bromohexadecanoic acid |
|---|---|
| Synonyms |
Hexadecanoic acid, 2-bromo-
2-bromopalmitate 2-Bromopalmitic acid UNII:7EI4G5X28Z 2-bromopalmitate,(+-)-isomer 2-bromo-hexadecanoic acid Hexadecanoic acid,2-bromo EINECS 242-137-0 MFCD00004215 bromopalmitic acid 2-Bromohexadecanoic acid |
| Description | 2-Bromohexadecanoic acid (2-Bromopalmitic acid) can be converted to 2-bromopalmitate (2-BP). 2-BP is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-BP inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 403.4±18.0 °C at 760 mmHg |
| Melting Point | 52-54 °C |
| Molecular Formula | C16H31BrO2 |
| Molecular Weight | 335.32 |
| Flash Point | 197.8±21.2 °C |
| Exact Mass | 334.150726 |
| PSA | 37.30000 |
| LogP | 7.76 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.480 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2915900090 |
|
~%
18263-25-7 |
| Literature: Journal of the Chemical Society, , vol. 87, p. 1901 Chemische Berichte, , vol. 25, p. 486 Chemische Berichte, , vol. 24, p. 939 |
|
~%
18263-25-7 |
| Literature: Yakugaku Zasshi, , vol. 61, p. 406;dtsch.Ref.S.127 Chem.Abstr., , p. 9356 |
| Precursor 2 | |
|---|---|
| DownStream 10 | |
![(2S)-2-[[(2S)-2-aminohexadecanoyl]amino]-2-[(3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid structure](https://www.chemsrc.com/caspic/486/112139-25-0.png)
![(2S)-2-[[(2R)-2-aminohexadecanoyl]amino]-2-[(3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid structure](https://www.chemsrc.com/caspic/034/112139-24-9.png)
| HS Code | 2915900090 |
|---|---|
| Summary | 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0% |