l-3-hydroxy-n-methylmorphinan dihydrate

l-3-hydroxy-n-methylmorphinan dihydrate Structure
l-3-hydroxy-n-methylmorphinan dihydrate structure
Common Name l-3-hydroxy-n-methylmorphinan dihydrate
CAS Number 5985-38-6 Molecular Weight 443.48800
Density N/A Boiling Point 410.4ºC at 760 mmHg
Molecular Formula C21H33NO9 Melting Point N/A
MSDS Chinese USA Flash Point 11ºC
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Sensitivity to the discriminative stimulus and antinociceptive effects of mu opioids: role of strain of rat, stimulus intensity, and intrinsic efficacy at the mu opioid receptor.

J. Pharmacol. Exp. Ther. 289 , 965, (1999)

Effects of low (butorphanol, nalbuphine)-, intermediate (buprenorphine)-, and high (morphine, levorphanol)-efficacy mu opioids were examined in F344, Sprague-Dawley (SD), Long-Evans (LE), and Lewis rats using a tail withdrawal and a drug discrimination proced...

Characterization and distribution of a cloned rat mu-opioid receptor.

J. Neurochem. 64 , 14-24, (1995)

We have cloned and expressed a rat brain cDNA, TS11, that encodes a mu-opioid receptor based on pharmacological, physiological, and anatomical criteria. Membranes were prepared from COS-7 cells transiently expressing TS11 bound [3H]diprenorphine with high aff...