l-3-hydroxy-n-methylmorphinan dihydrate

Modify Date: 2025-08-20 18:09:03

l-3-hydroxy-n-methylmorphinan dihydrate structure	Common Name	l-3-hydroxy-n-methylmorphinan dihydrate
	CAS Number	5985-38-6	Molecular Weight	443.48800
	Density	N/A	Boiling Point	410.4ºC at 760 mmHg
	Molecular Formula	C₂₁H₃₃NO₉	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	11ºC
	Symbol	GHS06, GHS08	Signal Word	Danger

Name	l-3-hydroxy-n-methylmorphinan dihydrate
Synonym	More Synonyms

Boiling Point	410.4ºC at 760 mmHg
Molecular Formula	C₂₁H₃₃NO₉
Molecular Weight	443.48800
Flash Point	11ºC
Exact Mass	443.21600
PSA	156.99000
LogP	0.76710

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD1924200

CAS REGISTRY NUMBER :: 5985-38-6

LAST UPDATED :: 199012

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C17-H23-N-O.C4-H6-O6.2H2-O

MOLECULAR WEIGHT :: 443.55

WISWESSER LINE NOTATION :: T6 G665/FP 2AF P FX ONT&TTJ IQ O1 &QVYQYQVQ &QH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 85,387,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 85,387,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 23 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 85,387,1951

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H312 + H332-H317-H334-H360
Precautionary Statements	Missing Phrase - N15.00950417-P201-P261-P280-P284-P308 + P313
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T,F
Risk Phrases	R61
Safety Phrases	53-22-36/37-45-16-7
RIDADR	UN 1544 6.1/PG 3
RTECS	QD1924200

l-DROMORAN TARTRATE

CAS#:125-72-4

l-3-hydroxy-n-m...

CAS#:5985-38-6

Literature: MALLINCKRODT INC. Patent: WO2006/23669 A2, 2006 ; Location in patent: Page/Page column 5-8 ;

Precursor 1
CAS#:125-72-4 l-DROMORAN TARTRATE
DownStream 0

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Effects of low (butorphanol, nalbuphine)-, intermediate (buprenorphine)-, and high (morphine, levorphanol)-efficacy mu opioids were examined in F344, Sprague-Dawley (SD), Long-Evans (LE), and Lewis ra...

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L-3-HYDROXY-N-METHYLMORPHINAN

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l-3-hydroxy-n-methylmorphinan dihydrate

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Articles2

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.