1-Nitropyrene
1-Nitropyrene structure
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Common Name | 1-Nitropyrene | ||
|---|---|---|---|---|
| CAS Number | 5522-43-0 | Molecular Weight | 247.248 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 445.5±14.0 °C at 760 mmHg | |
| Molecular Formula | C16H9NO2 | Melting Point | 153-155 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 223.5±12.9 °C | |
| Symbol |
GHS08 |
Signal Word | Warning | |
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Determination of descriptors for polycyclic aromatic hydrocarbons and related compounds by chromatographic methods and liquid-liquid partition in totally organic biphasic systems.
J. Chromatogr. A. 1361 , 240-54, (2014) Retention factors on several columns and at various temperatures using gas chromatography and from reversed-phase liquid chromatography on a SunFire C18 column with various mobile phase compositions containing acetonitrile, methanol and tetrahydrofuran as str... |
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Combination of precolumn nitro-reduction and ultraperformance liquid chromatography with fluorescence detection for the sensitive quantification of 1-nitronaphthalene, 2-nitrofluorene, and 1-nitropyrene in meat products.
J. Agric. Food Chem. 63(12) , 3161-7, (2015) Carcinogenic nitropolycyclic aromatic hydrocarbons (nitro-PAHs) are ubiquitous in the ambient environment. They are emitted predominantly from internal combustion engines and by reacting polycyclic aromatic hydrocarbons with nitrogen oxide. The emerging evide... |
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Differential chemokine induction by 1-nitropyrene and 1-aminopyrene in bronchial epithelial cells: importance of the TACE/TGF-α/EGFR-pathway.
Environ. Toxicol. Pharmacol. 35(2) , 235-9, (2013) 1-nitropyrene (1-NP), a common PAH in diesel exhaust, and its amine metabolite 1-aminopyrene (1-AP) induce distinctly different chemokine-responses in bronchial epithelial cells (BEAS-2B) characterized by increases in CXCL8 and CCL5, respectively. Tumor necro... |
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Organic pollution and genotoxicity of sediments of the Palun marshes (Berre lagoon, France).
J. Environ. Qual. 39(2) , 558-67, (2010) The impact of industrial, rural, and urban activities on two runnels (B1, B2, and B3 from Beausset runnel and V1 and V2 from Vallat du Ceinturon runnel) located in the Palun marshes (Berre lagoon, France) was evaluated by analyzing 16 polycyclic aromatic hydr... |
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Determination of 1-hydroxypyrene in human urine by HPLC with electrochemical detection at a boron-doped diamond film electrode.
Anal. Bioanal. Chem 404(3) , 693-9, (2012) A high-performance liquid chromatographic method with electrochemical detection (HPLC-ED) at a boron-doped diamond film electrode with preliminary separation and preconcentration by solid-phase extraction (SPE) has been developed for the determination of 1-hy... |
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Mechanisms of chemokine responses by polycyclic aromatic hydrocarbons in bronchial epithelial cells: sensitization through toll-like receptor-3 priming.
Toxicol. Lett. 219(2) , 125-32, (2013) We have previously observed that 1-nitropyrene (1-NP) and its amine metabolite 1-aminopyrene (1-AP) induce differential chemokine responses in human bronchial epithelial cells (BEAS-2B) characterized by maximum responses for CXCL8 (IL-8) and CCL5 (RANTES), re... |
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Photodegradation mechanisms of 1-nitropyrene, an environmental pollutant: the effect of organic solvents, water, oxygen, phenols, and polycyclic aromatics on the destruction and product yields.
J. Phys. Chem. A 116(14) , 3652-64, (2012) This work describes studies of the photodegradation mechanism of 1-nitropyrene (1-NO(2)Py) in a chemical model system consisting of an organic solvent and known constituents of an aerosol particle. Photoproducts such as 1-hydroxypyrene (1-OHPy), 1-hydroxy-x-n... |
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AhR-dependent secretion of PDGF-BB by human classically activated macrophages exposed to DEP extracts stimulates lung fibroblast proliferation.
Toxicol. Appl. Pharmacol. 285 , 170-8, (2015) Lung diseases are aggravated by exposure to diesel exhaust particles (DEPs) found in air pollution. Macrophages are thought to play a crucial role in lung immune response to these pollutants, even if the mechanisms involved remain incompletely characterized. ... |
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Antimutagenic potential of harpagoside and Harpagophytum procumbens against 1-nitropyrene.
Pharmacogn. Mag. 11 , S29-36, (2015) 1-nitropyrene (1-NPy) is one of the most abundant nitro-polycyclic aromatic hydrocarbons particularly in diesel exhausts. It is a mutagenic and carcinogenic pollutant very widespread in the environment. So the discovery of antimutagenic agents is essential. H... |
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Sensitivity of Salmonella YG5161 for detecting PAH-associated mutagenicity in air particulate matter.
Environ. Mol. Mutagen. 55(6) , 510-7, (2014) The Salmonella/microsome assay is the most used assay for the evaluation of air particulate matter (PM) mutagenicity and a positive correlation between strain TA98 responses and benzo[a]pyrene (B[a]P) levels in PM has been found. However, it seems that the ma... |