Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-Nitropyrene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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5522-43-0

5522-43-0 structure

Name: 1-Nitropyrene
Chemical Name: 1-Nitropyrene
CAS Number: 5522-43-0
Molecular Formula: C₁₆H₉NO₂
Molecular Weight: 247.248
Catalog: Chemical reagent Organic reagent Nitro compound
Create Date: 2018-06-09 17:40:06
Modify Date: 2025-08-21 23:14:32

Name	1-Nitropyrene
Synonyms	1-nitro-pyrene Pyrene,1-nitro Nitropyrene,Mono-,Di-,Tri-Tetra,isomers 3-Nitropyrene 1-Nitropyrene NITROPYRENE 1-nitropyrne EINECS 226-868-2 MFCD00004138 Pyrene, 1-nitro-

Density	1.4±0.1 g/cm3
Boiling Point	445.5±14.0 °C at 760 mmHg
Melting Point	153-155 °C(lit.)
Molecular Formula	C₁₆H₉NO₂
Molecular Weight	247.248
Flash Point	223.5±12.9 °C
Exact Mass	247.063324
PSA	45.82000
LogP	4.90
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.871
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UR2480000

CHEMICAL NAME :: Pyrene, 1-nitro-

CAS REGISTRY NUMBER :: 5522-43-0

BEILSTEIN REFERENCE NO. :: 1882811

LAST UPDATED :: 199712

DATA ITEMS CITED :: 65

MOLECULAR FORMULA :: C16-H9-N-O2

MOLECULAR WEIGHT :: 247.26

WISWESSER LINE NOTATION :: L666 B6 2AB PJ DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 ug/m3/6H/13W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Liver - changes in liver weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 396 mg/kg/16W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 mg/kg/4W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 160 mg/kg/10W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1575 mg/kg/6W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 198 mg/kg/8W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 99 mg/kg/8W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1780 mg/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 160 mg/kg/10W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - thyroid tumors Reproductive - Tumorigenic effects - testicular tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 95566 ug/kg/4W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 91857 ug/kg/4W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 29671 ug/kg/4W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 495 mg/kg/8W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: Morphological transformation

TYPE OF TEST :: DNA adduct

TYPE OF TEST :: Sister chromatid exchange

TYPE OF TEST :: DNA damage

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rabbit Lung

DOSE/DURATION :: 2500 ng/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 175,259,1986 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,321,1989 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,321,1989 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,321,1989

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H351
Precautionary Statements	P281
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22;R40
Safety Phrases	S22-S36/37/39-S45-S36/37
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UR2480000
HS Code	2904209090

129-00-0

~98%

5522-43-0

Literature: Braken-van Leersum, A. M. van den; Tintel, C.; Zelfde, M. van't; Cornelisse, J.; Lugtenburg, J. Recueil des Travaux Chimiques des Pays-Bas, 1987 , vol. 106, # 4 p. 120 - 128

129-00-0

~2%

34244-15-0

5522-43-0

Literature: Journal of Organic Chemistry, , vol. 53, # 15 p. 3548 - 3553

1606-67-3

5522-43-0

42397-65-9

42397-64-8

Detail

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 5 p. 1992 - 1994

30269-04-6

5522-43-0

42397-65-9

42397-64-8

Detail

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 5 p. 1992 - 1994

14923-84-3

5522-43-0

42397-65-9

42397-64-8

Detail

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 5 p. 1992 - 1994

92821-64-2

5522-43-0

42397-65-9

42397-64-8

Detail

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 5 p. 1992 - 1994

129-00-0

~37%

5522-43-0

1785-51-9

2304-85-0

Detail

Literature: Russian Journal of Organic Chemistry, , vol. 34, # 8 p. 1165 - 1171

129-00-0

64-19-7

5522-43-0

Literature: Justus Liebigs Annalen der Chemie, , vol. 531, p. 1,33, 43, 46, 107, 121, 123

129-00-0

7697-37-2

64-19-7

5522-43-0

Literature: Kogyo Kagaku Zasshi, , vol. 55, p. 623 Chem.Abstr., , p. 2401

Precursor 7
129-00-0 1606-67-3 30269-04-6 14923-84-3
92821-64-2 64-19-7 7697-37-2
DownStream 10
42397-65-9 42397-64-8 75321-20-9 22755-15-3
5315-79-7 129944-95-2 36171-39-8 1606-67-3
85628-24-6 86674-51-3

HS Code	2904209090
Summary	2904209090 derivatives containing only nitro or only nitroso groups。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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