Scoparone
Scoparone structure
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Common Name | Scoparone | ||
|---|---|---|---|---|
| CAS Number | 120-08-1 | Molecular Weight | 206.195 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 369.2±42.0 °C at 760 mmHg | |
| Molecular Formula | C11H10O4 | Melting Point | 145°C | |
| MSDS | Chinese USA | Flash Point | 166.8±27.9 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Green tea inhibited the elimination of nephro-cardiovascular toxins and deteriorated the renal function in rats with renal failure.
Sci. Rep. 5 , 16226, (2015) Chronic kidney disease (CKD) is a major health problem worldwide. Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are highly protein-bound nephro-cardiovascular toxins, which are not efficiently removed through hemodialysis. The renal excretions of IS and PCS... |
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7-substituted coumarins inhibit proliferation and migration of laryngeal cancer cells in vitro.
Anticancer Res. 33(10) , 4347-56, (2013) Coumarins are a large group of naturally-occurring compounds with a wide range of biological properties, including anticancer activity. 7-Substituted coumarins (umbelliferone, scoparone, and herniarin) were analyzed for their potential anticancer activity aga... |
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Effects of scoparone on dopamine release in PC12 cells.
Fitoterapia 81(6) , 497-502, (2010) The effects of scoparone on dopamine release in PC12 cells were investigated. Scoparone at 50-200 microM increased dopamine release into the culture medium. However, the released levels of dopamine by scoparone were not altered in the absence of extracellular... |
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Determination and pharmacokinetics of 6,7-dimethoxycoumarin in rat plasma after intragastric administration of different decoctions of yinchenhao tang.
J. Chromatogr. Sci. 45(8) , 544-8, (2007) A simple and sensitive reversed-phase high-performance liquid chromatography method with UV detection is developed and validated for the determination of 6,7-dimethoxycoumarin in rat plasma and comparative analysis of its pharmacokinetics after intragastric a... |
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[Study on distributed patterns of scoparone and ayapin in Dendrobium species from Yunnan].
Zhongguo Zhong Yao Za Zhi 38(21) , 3691-5, (2013) An HPLC method for determination of scoparone and ayapin was established for investigating the distributed patterns of scoparone and ayapin in 37 species of Dendrobium. The contents of scoparone and ayapin in varied collected samples were determined by the es... |
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[A new natural product from root of Angelica dahurica cv. Qibaizhi].
Zhongguo Zhong Yao Za Zhi 37(16) , 2400-7, (2012) To study the chemical constituents of the root of Angelica dahurica cv. Qibaizhi.The compounds were isolated and purified by the methods of solvent extraction and chromatographic technique, and their structures were identified on the basis of the analyses of ... |
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[Studies on the chemical constituents from Lobelia chinensis].
Zhong Yao Cai 33(11) , 1721-4, (2010) To study the chemical constituents of the full plant of Lobelia chinensis.The compounds were isolated and purified using several column chromatographic methods. Their structures were elucidated based on their physicochemical properties and spectral data.Twelv... |
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[Main chemical components for clearing heat and relieving sore throat in different germplasm of Canarium album].
Zhongguo Zhong Yao Za Zhi 35(6) , 669-72, (2010) To screen the representing components in different germplasms of Canarium album and determine the content by HPLC for laying the foundation for the quality specification.Gallic acid and scopoletin and scoparone were chosen as the main chemical components for ... |
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Protective effects of coumarin and coumarin derivatives against carbon tetrachloride-induced acute hepatotoxicity in rats.
Exp. Toxicol. Pathol. 63 , 325-330, (2011) The comparison of the antioxidant activity of some coumarins with their molecular structure is well determined. However, the protective function of coumarins with various chemical structures against liver toxicity has not yet been well established. Therefore,... |
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[Isolation and identification of chemical constituents from peels of Citrus changshan-huyou Y.B. Chang].
Beijing Da Xue Xue Bao. 41(5) , 575-7, (2009) To study the chemical constituents of the peels collected from Citrus changshan-huyou Y. B. Chang, and further screen the bioactive components as the lead structures.These compounds were isolated by repeated flash column chromatography on silica gel and Sepha... |