5-Hydroxydecanoate sodium
5-Hydroxydecanoate sodium structure
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Common Name | 5-Hydroxydecanoate sodium | ||
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| CAS Number | 71186-53-3 | Molecular Weight | 210.24600 | |
| Density | N/A | Boiling Point | 320.8ºC at 760 mmHg | |
| Molecular Formula | C10H19NaO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 162ºC | |
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CYP-epoxygenases contribute to A2A receptor-mediated aortic relaxation via sarcolemmal KATP channels.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 303(10) , R1003-10, (2012) Previously, we have shown that A(2A) adenosine receptor (A(2A)AR) mediates aortic relaxation via cytochrome P-450 (CYP)-epoxygenases. However, the signaling mechanism is not understood properly. We hypothesized that ATP-sensitive K(+) (K(ATP)) channels play a... |
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Is preconditioning by oxytocin administration mediated by iNOS and/or mitochondrial K(ATP) channel activation in the in vivo anesthetized rabbit heart?
Life Sci. 90(19-20) , 763-9, (2012) Oxytocin (OXT) pretreatment protects the heart during ischemia-reperfusion injury by activating ATP-dependent potassium (K(ATP)) channels. The aim of the current study was to elucidate the roles of nitric oxide synthaseNOS and myocardial biochemistry in the c... |
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Mitochondrial K+ channels are involved in ischemic postconditioning in rat hearts.
J. Physiol. Sci. 62(4) , 325-32, (2012) The mitochondrial calcium-activated potassium channel (mitoK(Ca)) and the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) are both involved in cardiac preconditioning. Here, we examined whether these two channels are also involved in ischemic or ph... |
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[Cyclosporin A-sensitive mitochondrial pore as a target of cardioprotective action of hydrogen sulfide donor].
Ross. Fiziol. Zh. Im. I. M. Sechenova 99(2) , 261-72, (2013) In experiments on a model of ischemia-reperfusion in Langendorff isolated rat hearts and isolated mitochondria we studied the role of hydrogen sulfide donor - sodium hydrosulfide (NaHS, 7.4 mg/kg) in modulating the sensitivity ofmitochondrial permeability tra... |
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Opening of astrocytic mitochondrial ATP-sensitive potassium channels upregulates electrical coupling between hippocampal astrocytes in rat brain slices.
PLoS ONE 8(2) , e56605, (2013) Astrocytes form extensive intercellular networks through gap junctions to support both biochemical and electrical coupling between adjacent cells. ATP-sensitive K(+) (K(ATP)) channels couple cell metabolic state to membrane excitability and are enriched in gl... |
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Isoflurane decreases death of human embryonic stem cell-derived, transcriptional marker Nkx2.5(+) cardiac progenitor cells.
Acta Anaesthesiol. Scand. 55(9) , 1124-31, (2011) Cardiac progenitor cells (CPCs) derived from human embryonic stem cells (hESCs) can multiply and generate cardiomyocytes, offering their tremendous potential for cardiac regenerative therapy. However, poor survival under stressful conditions is a major hurdle... |
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Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs.
Cardiovasc. Drugs Ther. 26(3) , 195-204, (2012) Despite favorable metabolic and vascular effects, thiazolidinedione (TZD) drugs have not convincingly reduced cardiovascular mortality in clinical trials, raising the possibility of countervailing, off-target effects. We previously showed that TZDs block card... |
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A possible subcellular mechanism underlying the "French paradox": the opening of mitochondrial K(ATP) channels.
Appl. Physiol. Nutr. Metab. 36(5) , 768-72, (2011) A reduction in the risk of coronary heart disease has been associated to moderate red wine consumption. We tested whether a nonalcoholic red wine extract would open mitochondrial K(ATP) channels in guinea pig myocytes. The opening of mitochondrial K(ATP) chan... |
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The neuroprotective effect of diazoxide is mediated by mitochondrial ATP-dependent potassium channels in a rat model of acute subdural hematoma.
J. Clin. Neurosci. 20(1) , 144-7, (2013) Acute subdural hematoma (ASDH) results in neuronal death due to mitochondrial dysfunction and a subsequent cascade of apoptotic and necrotic events. We previously demonstrated that mitochondrial ATP-dependent potassium (mitoK(ATP)) channels have a major role ... |
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Skeletal muscle post-conditioning by diazoxide, anti-oxidative and anti-apoptotic mechanisms.
Mol. Biol. Rep. 39(12) , 11093-103, (2012) Pretreatment with diazoxide, K(ATP) channel opener, increases tissue tolerance against ischemia reperfusion (IR) injury. In clinical settings pretreatment is rarely an option therefore we evaluated the effect of post-ischemic treatment with diazoxide on skele... |