Phenylhydrazine hydrochloride

Phenylhydrazine hydrochloride Structure
Phenylhydrazine hydrochloride structure
Common Name Phenylhydrazine hydrochloride
CAS Number 59-88-1 Molecular Weight 144.602
Density 1.125g/cm3 Boiling Point 243ºC at 760 mmHg
Molecular Formula C6H9ClN2 Melting Point 250-254 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 115.4ºC
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

Characterization of a Functional Role of the Bradyrhizobium japonicum Isocitrate Lyase in Desiccation Tolerance.

Int. J. Mol. Sci. 16 , 16695-709, (2015)

Bradyrhizobium japonicum is a nitrogen-fixing symbiont of soybean. In previous studies, transcriptomic profiling of B. japonicum USDA110, grown under various environmental conditions, revealed the highly induced gene aceA, encoding isocitrate lyase (ICL). The...

A Chemical Screening Approach to Identify Novel Key Mediators of Erythroid Enucleation.

PLoS ONE 10 , e0142655, (2015)

Erythroid enucleation is critical for terminal differentiation of red blood cells, and involves extrusion of the nucleus by orthochromatic erythroblasts to produce reticulocytes. Due to the difficulty of synchronizing erythroblasts, the molecular mechanisms u...

Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.

Gastroenterology 146(5) , 1325-38, (2014)

The liver has one of the highest rates of heme synthesis of any organ. More than 50% of the heme synthesized in the liver is used for synthesis of P450 enzymes, which metabolize exogenous and endogenous compounds that include natural products, hormones, drugs...

Direct catalytic asymmetric reductive amination of simple aromatic ketones.

Org. Lett. 15(17) , 4354-7, (2013)

A green method for chiral amine synthesis, the direct catalytic asymmetric reductive amination, was developed. Phenylhydrazide is an ideal nitrogen source for reductive amination. Molecular sieves play dual roles in this reaction. They help to remove H2O to f...

The oxidation of phenylhydrazine by tyrosinase.

Appl. Biochem. Biotechnol. 169(8) , 2420-9, (2013)

Tyrosinase was found to catalyze the oxidation of phenylhydrazine to phenol in a reaction that did not resemble those typically performed by tyrosinase. The kinetics of this reaction was investigated by measuring the initial velocity of the formation of pheno...

In situ observation of ninhydrin and phenylhydrazine reaction in solution by FTIR.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 113 , 297-301, (2013)

The current work was performed for hydrazone formation reaction of ninhydrin with phenylhydrazine in chloroform by using "background defining method" in FTIR liquid cell. The method allowed following the consumption and formation of the reagent and product at...

Synthesis and bioactivity of pyrazole acyl thiourea derivatives.

Molecules 17(5) , 5139-50, (2012)

Sixteen novel pyrazole acyl thiourea derivatives 6 were synthesized from monomethylhydrazine (phenylhydrazine) and ethyl acetoacetate. The key 5-chloro-3-methyl-1-substituted-1H-pyrazole-4-carbonyl chloride intermediates 4 were first generated in four steps t...

Transfection of rodent malaria parasites.

Methods Mol. Biol. 923 , 99-125, (2013)

Gene manipulation is an invaluable tool to investigate and understand the biology of an organism. Although this technology has been applied to both the human and rodent malarial parasites (RMP), Plasmodium berghei in particular offers a more robust system due...

Novel antimicrobial organic thermal stabilizer and co-stabilizer for rigid PVC.

Molecules 17(7) , 7927-40, (2012)

Biologically active N-benzoyl-4-(N-maleimido)-phenylhydrazide (BMPH) was synthesized and its structure was confirmed by elemental analysis and various spectral tools. It was examined as a thermal stabilizer and co-stabilizer for rigid poly (vinyl chloride) at...

Hematopoietic effect of Bacillus subtilis-fermented antler extract on phenylhydrazine-induced hemolytic anemia in Sprague-Dawley rats.

J. Med. Food 15(9) , 774-80, (2012)

This study examined the effect of fermentation on the ability of antler to act as a stimulator of hematopoietic activity. Hemolytic anemia was induced by phenylhydrazine (PHZ) in female Sprague-Dawley rats. The vehicle or antler extract (nonfermented or ferme...