Dimethyl but-2-ynedioate
Dimethyl but-2-ynedioate structure
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Common Name | Dimethyl but-2-ynedioate | ||
|---|---|---|---|---|
| CAS Number | 762-42-5 | Molecular Weight | 142.109 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 204.3±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H6O4 | Melting Point | -18 °C | |
| MSDS | Chinese USA | Flash Point | 86.1±0.0 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Dehydrogenative TEMPO-Mediated Formation of Unstable Nitrones: Easy Access to N-Carbamoyl Isoxazolines.
Chemistry 21 , 12053-60, (2015) N-carbamoyl nitrones represent an important class of reagents for the synthesis of a variety of natural and biologically active compounds. These compounds are generally converted into valuable 4-isoxazolines upon cyclization reaction with dipolarophiles. Howe... |
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A Mechanochromic Luminescent Dye Exhibiting On/Off Switching by Crystalline-Amorphous Transitions.
Chem. Asian J. 10 , 1698-702, (2015) A mechanochromic luminescent dye based on a simple aminomaleimide skeleton was readily synthesized in a one-pot process. It exhibited an on/off mechanochromic luminescent switching property dependent on external stimuli, unlike a traditional mechanochromic co... |
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Development of a gold-multifaceted catalysis approach to the synthesis of highly substituted pyrroles: mechanistic insights via Huisgen cycloaddition studies.
J. Org. Chem. 78(3) , 920-34, (2013) A novel gold-catalyzed method for the regioselective synthesis of highly substituted pyrroles directly from oximes and alkynes was developed via independent optimization of two key steps of the process. Importantly, a cationic gold(I) species was shown to act... |
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Microwave assisted condensation reactions of 2-aryl hydrazonopropanals with nucleophilic reagents and dimethyl acetylenedicarboxylate.
Molecules 12(8) , 2061-79, (2007) The reaction of methyl ketones 1a-g with dimethylformamide dimethylacetal (DMFDMA) afforded the enaminones 2a-g, which were coupled with diazotized aromatic amines 3a,b to give the corresponding aryl hydrazones 6a-h. Condensation of compounds 6a-h with some a... |
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Three-component reaction between triphenylphosphine, dialkyl acetylenedicarboxylates and urea or N-methylurea.
Mol. Divers. 10(1) , 23-7, (2006) The stabilized phosphoranes, obtained from the three-component reaction between dialkyl acetylenedicarboxylates and urea or N-methylurea in the presence of triphenylphosphine, undergo a smooth reaction in boiling toluene to produce iminophosphoranes in good y... |
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Smart coumarin-tagged imprinted polymers for the rapid detection of tamoxifen.
Anal. Bioanal. Chem 408 , 1855-61, (2016) A signalling molecularly imprinted polymer was synthesised for easy detection of tamoxifen and its metabolites. 6-Vinylcoumarin-4-carboxylic acid (VCC) was synthesised from 4-bromophenol to give a fluorescent monomer, designed to switch off upon binding of ta... |
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Multicomponent reactions of dimethyl methoxymalonate and dialkyl acetylenedicarboxylate in the presence of N-nucleophiles: one-pot synthesis of 2H-pyridinyl-2-butenedioates in water.
Mol. Divers. 14(3) , 605-9, (2010) An efficient synthesis of 2H-pyridinyl-2-butenedioate derivatives via reaction of dimethyl methoxymalonate and dialkyl acetylenedicarboxylate in the presence of N-nucleophiles in water as a solvent is described. |
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Facile synthesis of highly substituted 3-aminofurans from thiazolium salts, aldehydes, and dimethyl acetylenedicarboxylate.
J. Org. Chem. 70(22) , 8919-23, (2005) [reaction: see text] A facile preparation of 3-aminofuran derivatives via multicomponent reactions of thiazole carbenes, aldehydes, and dimethyl acetylenedicarboxylate (DMAD) is reported. In this process, the thiazole carbenes, generated in situ from thiazoli... |
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Structure-activity comparison of the cytotoxic properties of diethyl maleate and related molecules: identification of diethyl acetylenedicarboxylate as a thiol cross-linking agent.
Chem. Res. Toxicol. 24(1) , 81-8, (2011) Many α,β-unsaturated carbonyl compounds are used in biochemical and medical research. Their biological effects are due in large part to their electrophilic properties, whereby they undergo reaction with nucleophilic sites in proteins and nucleic acids. Here, ... |
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Novel multicomponent reaction of [60]fullerene: the first example of 1,4-dipolar cycloaddition reaction in fullerene chemistry.
Org. Biomol. Chem. 4(22) , 4063-4, (2006) The novel multicomponent reaction of [60]fullerene with dimethyl acetylenedicarboxylate and isoquinoline, quinoline or substituted quinolines was investigated. This type of reaction presents the first example of a 1,4-dipolar cycloaddition reaction in fullere... |