Rosmarinic acid
Rosmarinic acid structure
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Common Name | Rosmarinic acid | ||
|---|---|---|---|---|
| CAS Number | 20283-92-5 | Molecular Weight | 360.315 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 694.7±55.0 °C at 760 mmHg | |
| Molecular Formula | C18H16O8 | Melting Point | 171-175 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 254.5±25.0 °C | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
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Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity.
Br. J. Nutr. 113(5) , 770-82, (2015) Type 1 diabetes (T1D), an autoimmune inflammatory disorder, develops as a consequence of pancreatic β-cell destruction and results in hyperglycaemia. Since current T1D therapy mainly involves insulin replacement, the aim of the present study was to evaluate t... |
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The hepatoprotection of caffeic acid and rosmarinic acid, major compounds of Perilla frutescens, against t-BHP-induced oxidative liver damage.
Food Chem. Toxicol. 55 , 92-9, (2013) Perilla frutescens leaves are often used in East Asian gourmet food. In this study, we investigated the hepatoprotective effects of caffeic acid (CA), rosmarinic acid (RA), and their combination. P. frutescens contains 1.32μg CA/mg dry material (DM) and 26.84... |
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Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts.
Food Chem. 161 , 79-86, (2014) Antimicrobial properties of ethanol and water extracts from eight Asteraceae species were investigated against three Gram positive (Staphylococcus aureus, MRSA and Bacillus cereus) and two Gram negative (Escherichia coli and Salmonella typhimurium) bacterial ... |
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Centella asiatica and Its Fractions Reduces Lipid Peroxidation Induced by Quinolinic Acid and Sodium Nitroprusside in Rat Brain Regions.
Neurochem. Res. 40 , 1197-210, (2015) Oxidative stress has been implicated in several pathologies including neurological disorders. Centella asiatica is a popular medicinal plant which has long been used to treat neurological disturbances in Ayurvedic medicine. In the present study, we quantified... |
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Systemic exposure to and disposition of catechols derived from Salvia miltiorrhiza roots (Danshen) after intravenous dosing DanHong injection in human subjects, rats, and dogs.
Drug Metab. Dispos. 43(5) , 679-90, (2015) DanHong injection is a Danshen (Salvia miltiorrhiza roots)-based injectable solution for treatment of coronary artery disease and ischemic stroke. Danshen catechols are believed to be responsible for the injection's therapeutic effects. This study aimed to ch... |
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Poly(N-vinylimidazole/ethylene glycol dimethacrylate) for the purification and isolation of phenolic acids.
Anal. Chim. Acta 885 , 199-206, (2015) In this study we report the novel polymeric resin poly(N-vinyl imidazole/ethylene glycol dimethacrylate) for the purification and isolation of phenolic acids. The monomer to crosslinker ratio and the porogen composition were optimized for isolating phenolic a... |
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Impact of Hydrophobicity on Antioxidant Efficacy in Low-Moisture Food.
J. Agric. Food Chem. 63 , 5821-7, (2015) The polarity and partitioning of antioxidants (AOX) in lipid dispersions and bulk oils have a large impact on efficacy, but this has not yet been studied in low-moisture foods. Using a homologous series of rosmarinic esters as AOX in crackers, we determined t... |
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Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease.
J. Intern. Med. 276(5) , 470-85, (2014) The complement system is involved in many immune complex-mediated kidney diseases, yet its role in the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) has not been examined in detail.Screening of the glycoproteome of urine samples from AD... |
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A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Bioorg. Med. Chem. Lett. 19 , 4952-7, (2009) Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular oligomers and linear fibrils, which possess distinct biological ac... |
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Surfactant-coated graphitized multiwalled carbon nanotubes as the pseudostationary phase in electrokinetic chromatography for the analysis of phytochemical compounds in biological fluids.
Electrophoresis 36(7-8) , 1055-63, (2015) This report describes the use of surfactant-coated graphitized multiwalled carbon nanotubes (SC-GMWNTs) as a novel pseudostationary phase in CE with diode array detection for the determination of phenolic acids and tanshinones in herbal and urine samples. Sev... |