2,6-Difluorobenzoic acid

2,6-Difluorobenzoic acid Structure
2,6-Difluorobenzoic acid structure
Common Name 2,6-Difluorobenzoic acid
CAS Number 385-00-2 Molecular Weight 158.102
Density 1.4±0.1 g/cm3 Boiling Point 231.0±20.0 °C at 760 mmHg
Molecular Formula C7H4F2O2 Melting Point 157-161 °C(lit.)
MSDS Chinese USA Flash Point 93.5±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis of 2,6-difluoro-N-(3-[11C]methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide as a new potential PET agent for imaging of B-Raf(V600E) in cancers.

Bioorg. Med. Chem. Lett. 23(4) , 1017-21, (2013)

The authentic standard 2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide was synthesized from 2,6-difluorobenzoic acid and 3-amino-5-hydroxypyrazole in 9 steps with 1% overall chemical yield. Direct desmethylation of t...

Effect of diflubenzuron and its major degradation products on the growth of Euglena gracilis Z. and incorporation of glycine-U-14C in protein.

J. Environ. Sci. Health B 16(2) , 159-66, (1981)

Diflubenzuron (I) and its major degradation products 4-chlorophenyl urea (II), 2,6-difluorobenzoic acid (III) and 4-chloroaniline (IV) were tested for their activity on Euglena gracilis Z. The inhibition on the growth and on the incorporation of glycine-U-14C...

Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas.

J. Agric. Food Chem. 53(1) , 38-41, (2005)

Two series of benzoylphenylurea derivatives were synthesized as candidate propesticides by a nucleophilic addition reaction between 2,6-difluronbenzoyl isocyanate and N-substitutedaniline. The new compounds were identified by 1H NMR spectroscopy, electron ion...

Metabolism of the insecticide teflubenzuron in rats.

Xenobiotica 27(8) , 801-17, (1997)

1. The metabolic fate of the insecticide teflubenzuron, orally dosed to the male Wistar rat, was investigated. Particular attention was paid to the metabolic fate of the benzoyl and aniline moiety after hydrolysis of the urea bridge. 2. The 0-48-h urinary and...

Structure of calcium 2,6-difluorobenzoate dihydrate.

Acta Crystallogr. C 48 ( Pt 6) , 1015-8, (1992)

Ca2+.2C7H3O2F2-.2H2O, M(r) = 390.3, monoclinic, C2/c, a = 17.584 (4), b = 10.771 (3), c = 7.887 (2) A, beta = 91.28 (2) degrees, V = 1493 A3, Z = 4, Dm = 1.75, Dx = 1.74 g cm-3, lambda(Mo K alpha) = 0.71073 A, mu = 4.92 cm-1, F(000) = 792, T = 293 K, final R ...