2-Nitrobenzaldehyde

2-Nitrobenzaldehyde Structure
2-Nitrobenzaldehyde structure
Common Name 2-Nitrobenzaldehyde
CAS Number 552-89-6 Molecular Weight 151.12
Density 1.3±0.1 g/cm3 Boiling Point 268.2±0.0 °C at 760 mmHg
Molecular Formula C7H5NO3 Melting Point 42-44 °C(lit.)
MSDS Chinese USA Flash Point 144.0±15.4 °C
Symbol GHS07
GHS07
Signal Word Warning

A selective biomarker for confirming nitrofurazone residues in crab and shrimp using ultra-performance liquid chromatography-tandem mass spectrometry.

Anal. Bioanal. Chem 407 , 8971-7, (2015)

Reliably detecting nitrofurazone (NFZ) residues in farmed crab and shrimp was previously hindered by lack of appropriately specific analytical methodology. Parent NFZ rapidly breaks down in meat, and the commonly used side-chain metabolite, semicarbazide (SEM...

Determination of nitrofuran and chloramphenicol residues by high resolution mass spectrometry versus tandem quadrupole mass spectrometry.

Anal. Chim. Acta 862 , 41-52, (2015)

An ultra-high performance liquid chromatography based method, coupled to high resolution mass spectrometry (UHPLC-HRMS), was developed to permit the detection and quantification of various nitrofuran and chloramphenicol residues in a number of animal based fo...

Tenellin acts as an iron chelator to prevent iron-generated reactive oxygen species toxicity in the entomopathogenic fungus Beauveria bassiana.

FEMS Microbiol. Lett. 362 , 1-8, (2015)

Iron is an essential element for life. However, the iron overload can be toxic. Here, we investigated the significant increase of tenellin and iron-tenellin complex production in ferricrocin-deficient mutants of Beauveria bassiana. Our chemical analysis indic...

Generation of semicarbazide from natural azine development in foods, followed by reaction with urea compounds.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 32 , 1416-30, (2015)

This paper proposes a mechanism to explain the trace levels of natural semicarbazide occasionally observed in foods. The analytical derivative of semicarbazide, 2-nitrobenzaldehyde semicarbazone, is often measured as a metabolite marker to detect the widely b...

Fortified versus incurred residues: extraction of furazolidinone metabolite from prawn.

Anal. Bioanal. Chem 407 , 4535-40, (2015)

Most methods reported in the literature for determination of nitrofuran metabolites use the same extraction and derivatisation conditions to hydrolyse and extract the protein-bound residues from animal tissue. While undertaking certification of reference mate...

Oriented synthesis and in vitro anticancer activity of biquinazoline-2,2'-diones.

J. Comb. Chem. 12(1) , 195-9, (2010)

The synthesis of a series of biquinazoline-2,2'-diones starting from o-nitrobenzaldehydes, anilines, and triphosgene is presented. This general approach features a novel and easy way for access to the target products. The mechanistic course of the reaction su...

Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides.

Macromol. Biosci. 15(1) , 52-62, (2015)

To address the downside of conventional photo-patterning which can alter the chemical composition of protein scaffolds, we developed a non-covalent photo-patterning strategy for gelatin (denatured collagen) hydrogels that utilizes UV activated triple helical ...

Determination of trace level genotoxic impurities in small molecule drug substances using conventional headspace gas chromatography with contemporary ionic liquid diluents and electron capture detection.

J. Chromatogr. A. 1361 , 217-28, (2014)

Ionic liquids (ILs) were used as a new class of diluents for the analysis of two classes of genotoxic impurities (GTIs), namely, alkyl/aryl halides and nitro-aromatics, in small molecule drug substances by headspace gas chromatography (HS-GC) coupled with ele...

A one-step synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid esters from o-nitrobenzaldehydes.

J. Org. Chem. 75(10) , 3488-91, (2010)

A straightforward and efficient one-step procedure for the synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters is described. The simple reductive cyclization is carried out by treating various substituted o-nitrobenzaldehydes with inexpens...

A non-adiabatic quantum-classical dynamics study of the intramolecular excited state hydrogen transfer in ortho-nitrobenzaldehyde.

Phys. Chem. Chem. Phys. 13(32) , 14685-93, (2011)

In this study, we examined the quantitative relationship between centrally administered hypertonic saline (HS) concentrations and the expression of Fos-like immunoreactivity (FLI) in brain regions involved in the homeostasis of body fluids. The regions examin...