3-Amino-1-hydroxyadamantane

3-Amino-1-hydroxyadamantane Structure
3-Amino-1-hydroxyadamantane structure
Common Name 3-Amino-1-hydroxyadamantane
CAS Number 702-82-9 Molecular Weight 167.248
Density 1.3±0.1 g/cm3 Boiling Point 266.8±23.0 °C at 760 mmHg
Molecular Formula C10H17NO Melting Point 265 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 115.2±22.6 °C
Symbol GHS07
GHS07
Signal Word Warning

Adamantyl analogues of paracetamol as potent analgesic drugs via inhibition of TRPA1.

PLoS ONE 9(12) , e113841, (2014)

Paracetamol also known as acetaminophen, is a widely used analgesic and antipyretic agent. We report the synthesis and biological evaluation of adamantyl analogues of paracetamol with important analgesic properties. The mechanism of nociception of compound 6a...

Liquid chromatographic methods for the determination of vildagliptin in the presence of its synthetic intermediate and the simultaneous determination of pioglitazone hydrochloride and metformin hydrochloride.

Int. J. Biomed. Sci. 7(3) , 201-8, (2011)

Ozone fumigation was explored as a means for degrading organic fungicide residues on fresh produce. Fungicides sorbed onto model abiotic glass surfaces or onto grape berries were fumigated separately in a flow-through chamber. Gaseous ozone at a constant conc...

Further calculations on solubility of 3-amino-1-adamantanol in ethanol+ water binary solvent mixtures at various temperatures. Jouyban A, et al.

J. Mol. Liq. 219 , 211-215, (2016)

A Facile and Economical Method to Synthesize Vildagliptin. Deng Y, et al.

Lett. Org. Chem. 11(10) , 780-784, (2014)

NOVEL TRICYCLIC CYANOPYRROLIDINE DERIVATIVES AS DPP4 INHIBITORS: AN IMPROVED SYNTHESIS OF TRICYCLIC a-CYCNOPYRROLIDINE FROM CAMPHOR. Arumugam K and Anitha M.

Rasayan J. Chem. 6(3) , 230-237, (2013)

1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.

J. Med. Chem. 46 , 2774-2789, (2003)

Dipeptidyl peptidase IV (DPP-IV) inhibition has the potential to become a valuable therapy for type 2 diabetes. The synthesis and structure-activity relationship of a new DPP-IV inhibitor class, N-substituted-glycyl-2-cyanopyrrolidines, are described as well ...