5-Hydroxy-2-adamantone
5-Hydroxy-2-adamantone structure
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Common Name | 5-Hydroxy-2-adamantone | ||
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| CAS Number | 20098-14-0 | Molecular Weight | 166.217 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 296.5±33.0 °C at 760 mmHg | |
| Molecular Formula | C10H14O2 | Melting Point | >300 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 124.9±18.0 °C | |
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[Interspecific differences in kemantan pharmacokinetics].
Eksp. Klin. Farmakol. 57(6) , 48-50, (1994) The pharmacokinetics of the new immunostimulant kemantane, adamantane derivative, used in two species of animals (rats and rabbits) and man was studied. There were significant differences in the pharmacokinetics of kemantane and its active metabolite--adamant... |
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[Kemantane pharmacokinetics in rats].
Biull. Eksp. Biol. Med. 110(11) , 501-3, (1990) Pharmacokinetics of novel immunostimulating drug kamantane was studied by using gas-liquid chromatography in experiments on rats. It was found that kemantane biotransformed rapidly after oral administration with the forming of active metabolite. Kemantane and... |
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[The clinical pharmacokinetics of kemantane].
Farmakol. Toksikol. 54(1) , 57-9, (1991) The pharmacokinetics of a new Soviet-made immunostimulant kemantane, a derivative of adamantine, was studied by gas-liquid chromatography in patients with bronchial pathology. It was found that in the blood of the patients kemantane was not practically detect... |
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[Treatment of immunodeficient conditions caused by viral infection with the Soviet immunomodulator kemantan in patients with pulmonary tuberculosis].
Probl. Tuberk. (6) , 23-6, (1991) Observation of 219 patients with pulmonary tuberculosis was made to study the effect of acute respiratory viral infection (ARVI) on the course of the disease. The affected were divided into 2 groups: 136 subjects who had ARVI and 83 persons who did not have i... |
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Effect of adamantanone derivative possessing anti-HIV properties on the redox processes in the cytochrome P-450 system.
Dokl. Biochem. Biophys. 378 , 210-3, (2001)
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[The effect of kemantane on T-helpers and T-suppressors].
Zh. Mikrobiol. Epidemiol. Immunobiol. (9) , 66-7, (1991) The study of Kemantan on functionally alternative humoral immunity regulator cells: T-helpers and antigen-specific T-suppressors, including their induction, accumulation and functioning, was studied. Kemantan in doses of 0.2-200 mg/kg, introduced to the donor... |
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[The mitostatic and lymphotoxic action of kemantane and its effect on B-suppressors].
Zh. Mikrobiol. Epidemiol. Immunobiol. (6) , 63-5, (1991) The in vivo study of the influence of Kemantan on the growth of endogenous colonies in the spleen of sublethally (6 Gy) irradiated (CBA x C57BL/6J) F1 mice (mitostatic action) and on the capacity of transplanted lymphocytes of CBA mice for suppressing their m... |
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[The immunomodulator kemantan in the treatment of patients with exacerbated chronic obstructive bronchitis].
Lik. Sprava (4) , 73-6, (1992)
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Biocatalytic production of 5-hydroxy-2-adamantanone by P450cam coupled with NADH regeneration. Furuya T, et al.
J. Mol. Catal., B Enzym. 94 , 111-118, (2013)
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Application of shift reagents in the study of disubstituted derivatives of adamantane by NMR spectroscopy. Vodicka L, et al.
Collect. Czech. Chem. Commun. 40(1) , 293-299, (1975)
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