Biulleten' eksperimental'noi biologii i meditsiny 1990-11-01

[Kemantane pharmacokinetics in rats].

S S Boĭko, V P Zherdev, A A Dvorianinov, I Janku, E Buchar

Index: Biull. Eksp. Biol. Med. 110(11) , 501-3, (1990)

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Abstract

Pharmacokinetics of novel immunostimulating drug kamantane was studied by using gas-liquid chromatography in experiments on rats. It was found that kemantane biotransformed rapidly after oral administration with the forming of active metabolite. Kemantane and its metabolites are distributed rapidly from the blood to organs. The drug is eliminated from the organism of rats as metabolite.