Succinic acid
Succinic acid structure
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Common Name | Succinic acid | ||
|---|---|---|---|---|
| CAS Number | 110-15-6 | Molecular Weight | 118.088 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 236.1±13.0 °C at 760 mmHg | |
| Molecular Formula | C4H6O4 | Melting Point | 185 °C | |
| MSDS | Chinese USA | Flash Point | 110.9±16.3 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.
J. Chromatogr. A. 1361 , 265-76, (2014) This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse urine. Samples were obtained from a murine model that mimics... |
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Direct silylation of Trypanosoma brucei metabolites in aqueous samples and their GC-MS/MS analysis.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 134-8, (2014) A simple two-step method for the derivatization of polar compounds (lactate, alanine, glycerol, succinate and glucose) using hexamethyldisilazane (HMDS) and N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) was developed. This method allows direct derivatizat... |
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Lactic acid production from acidogenic fermentation of fruit and vegetable wastes.
Bioresour. Technol. 191 , 53-8, (2015) This work focused on the lactic acid production from acidogenic fermentation of fruit and vegetable wastes treatment. A long term completely stirred tank reactor (CSTR) lasting for 50 days was operated at organic loading rate (OLR) of 11 gVS/(L d) and sludge ... |
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MCL-1-independent mechanisms of synergy between dual PI3K/mTOR and BCL-2 inhibition in diffuse large B cell lymphoma.
Oncotarget 6 , 35202-17, (2015) The PI3K/AKT/mTOR axis promotes survival and is a frequently mutated pathway in cancer. Yet, inhibitors targeting this pathway are insufficient to induce cancer cell death as single agents in some contexts, including diffuse large B cell lymphoma (DLBCL). In ... |
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Synthesis of folate- pegylated polyester nanoparticles encapsulating ixabepilone for targeting folate receptor overexpressing breast cancer cells.
J. Mater. Sci. Mater. Med. 26 , 275, (2015) The aim of this study was the preparation of novel polyester nanoparticles based on folic acid (FA)-functionalized poly(ethylene glycol)-poly(propylene succinate) (PEG-PPSu) copolymer and loaded with the new anticancer drug ixabepilone (IXA). These nanopartic... |
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Differential expression of small RNAs under chemical stress and fed-batch fermentation in E. coli.
BMC Genomics 16 , 1051, (2015) Bacterial small RNAs (sRNAs) are recognized as posttranscriptional regulators involved in the control of bacterial lifestyle and adaptation to stressful conditions. Although chemical stress due to the toxicity of precursor and product compounds is frequently ... |
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Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers.
Nat. Commun. 6 , 6114, (2015) A(H1N1)pdm09 influenza A viruses predominated in the 2013-2014 USA influenza season, and although most of these viruses remain sensitive to Food and Drug Administration-approved neuraminidase (NA) inhibitors, alternative therapies are needed. Here we show tha... |
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Properties and extraction of pectin-enriched materials from sugar beet pulp by ultrasonic-assisted treatment combined with subcritical water.
Food Chem. 168 , 302-10, (2014) Pectin-enriched material (PEM) was extracted from sugar beet pulp using subcritical water combined with ultrasonic-assisted treatment. Optimisation of the reaction parameters for maximum extraction yield of PEM was carried out using response surface methodolo... |
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Physiology and pathophysiology of organic acids in cerebrospinal fluid.
J. Inherit. Metab. Dis. 16(4) , 648-69, (1993) Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarboxylic acids from the brain is a major route for removing th... |
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HMDB: a knowledgebase for the human metabolome.
Nucleic Acids Res. 37(Database issue) , D603-10, (2009) The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. Si... |