N-chlorosuccinimide
N-chlorosuccinimide structure
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Common Name | N-chlorosuccinimide | ||
|---|---|---|---|---|
| CAS Number | 128-09-6 | Molecular Weight | 133.533 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 200.5±23.0 °C at 760 mmHg | |
| Molecular Formula | C4H4ClNO2 | Melting Point | 148-150 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 75.1±22.6 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.
Pharm. Res. 32(5) , 1546-56, (2015) To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide (penetratin), all 5(6)-carboxytetramethylrhodamine-labeled,... |
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Induction of Local Secretory IgA and Multifunctional CD4⁺ T-helper Cells Following Intranasal Immunization with a H5N1 Whole Inactivated Influenza Virus Vaccine in BALB/c Mice.
Scand. J. Immunol. 81 , 305-17, (2015) Avian influenza subunit vaccines have been shown to be poorly immunogenic, leading to the re-evaluation of the immunogenic and dose-sparing potential of whole virus vaccines. In this study, we investigated the immune responses after one or two doses of intram... |
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Phosphoregulatory protein 14-3-3 facilitates SAC1 transport from the endoplasmic reticulum.
Proc. Natl. Acad. Sci. U. S. A. 112 , E3199-206, (2015) Most secretory cargo proteins in eukaryotes are synthesized in the endoplasmic reticulum and actively exported in membrane-bound vesicles that are formed by the cytosolic coat protein complex II (COPII). COPII proteins are assisted by a variety of cargo-speci... |
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Anti-adipogenic and antioxidant effects of the traditional Korean herbal formula Samchulgeonbi-tang: an in vitro study.
Int. J. Clin. Exp. Med. 8 , 8698-708, (2015) Here we report in vitro anti-adipogenic and antioxidant effects of Samchulgeonbi-tang (SCGBT), a traditional Korean herbal formula.3T3-L1 preadipocytes were differentiated into adipocytes with or without SCGBT. After differentiation, we measured Oil Red O sta... |
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Assembly of multiple cell gradients directed by three-dimensional microfluidic channels.
Lab Chip 15 , 3203-10, (2015) Active control over the cell gradient is essential for understanding biological systems and the reconstitution of the functionality of many types of tissues, particularly for organ-on-a-chip. Here, we propose a three-dimensional (3D) microfluidic strategy for... |
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Comparison of succinimidyl [(125)I]iodobenzoate with iodogen iodination methods to study pharmacokinetics and ADME of biotherapeutics.
Pharm. Res. 31(10) , 2810-21, (2014) To assess the application of succinimidyl iodobenzoate (SIB) iodination method in labeling biotherapeutics to study their pharmacokinetics (PK) and biodistribution.An IgG molecule (protein-01) and a 40 KDa protein (protein-02) were evaluated. Pharmacokinetics... |
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Yield, Quality, and Nutrient Concentrations of Strawberry (Fragaria ×ananassa Duch. cv. 'Sonata') Grown with Different Organic Fertilizer Strategies.
J. Agric. Food Chem. 63 , 5578-86, (2015) Four combinations of two solid organic fertilizers (Monterra Malt and chicken manure) applied before planting and two liquid organic fertilizers (broad bean and Pioner Hi-Fruit/K-Max) given through drip irrigation (fertigation) were compared with inorganic fe... |
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Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase.
Oncogene 34(3) , 281-9, (2015) Mdm2 is a critical negative regulator of the tumor suppressor protein p53. Mdm2 is an E3 ligase whose overexpression leads to functional inactivation of p53. Mdm2 protein stability is regulated by several mechanisms including RING (Really Interesting New Gene... |
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The COP9 signalosome is vital for timely repair of DNA double-strand breaks.
Nucleic Acids Res. 43 , 4517-30, (2015) The DNA damage response is vigorously activated by DNA double-strand breaks (DSBs). The chief mobilizer of the DSB response is the ATM protein kinase. We discovered that the COP9 signalosome (CSN) is a crucial player in the DSB response and an ATM target. CSN... |
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Ectromelia virus encodes an anti-apoptotic protein that regulates cell death.
Virology 475 , 74-87, (2014) Apoptosis serves as a powerful defense against damaged or pathogen-infected cells. Since apoptosis is an effective defense against viral infection, many viruses including poxviruses, encode proteins to prevent or delay apoptosis. Here we show that ectromelia ... |