allantoin
allantoin structure
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Common Name | allantoin | ||
|---|---|---|---|---|
| CAS Number | 97-59-6 | Molecular Weight | 158.115 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 478ºC | |
| Molecular Formula | C4H6N4O3 | Melting Point | 230 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 230-234°C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells.
MAbs 7(2) , 403-12, (2015) Linking the heavy chain (HC) and light chain (LC) genes required for monoclonal antibodies (mAb) production on a single cassette using 2A peptides allows control of LC and HC ratio and reduces non-expressing cells. Four 2A peptides derived from the foot-and-m... |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
PLoS ONE 10(3) , e0120950, (2015) Curcumin, a principle bioactive component of Curcuma longa L, is well known for its anti-hyperlipidemia effect. However, no holistic metabolic information of curcumin on hyperlipidemia models has been revealed, which may provide us an insight into the underly... |
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GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy.
Am. J. Physiol. Renal Physiol. 304(11) , F1317-24, (2013) Early diagnosis of diabetic nephropathy (DN) is difficult although it is of crucial importance to prevent its development. To probe potential markers and the underlying mechanism of DN, an animal model of DN, the db/db mice, was used and serum and urine metab... |
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Simultaneous quantification of purine and pyrimidine bases, nucleosides and their degradation products in bovine blood plasma by high performance liquid chromatography tandem mass spectrometry.
J. Chromatogr. A. 1356 , 197-210, (2014) Improved nitrogen utilization in cattle is important in order to secure a sustainable cattle production. As purines and pyrimidines (PP) constitute an appreciable part of rumen nitrogen, an improved understanding of the absorption and intermediary metabolism ... |
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Chromatin-mediated depression of fractionation performance on electronegative multimodal chromatography media, its prevention, and ramifications for purification of immunoglobulin G.
J. Chromatogr. A. 1374 , 145-55, (2014) Chromatin heteroaggregates comprising nucleosomal arrays, DNA, histone and non-histone host cell proteins contributed 28% of the host contaminant mass in an IgG cell culture harvest. A subset comprising soluble particles of 50-400nm was retained through its h... |
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Research on the immunosuppressive activity of ingredients contained in sunscreens.
Arch. Dermatol. Res. 307(3) , 211-8, (2015) The immunosuppressive properties of Benzophenone-4, an UV-filter and three ingredients, Allantoin, Bisabolol and Enoxolon used in sunscreen formulation, previously characterized as anti-inflammatory compounds, are studied. The results of this study demonstrat... |
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Feeding protein supplements in alfalfa hay-based lactation diets improves nutrient utilization, lactational performance, and feed efficiency of dairy cows.
J. Dairy Sci. 97(12) , 7716-28, (2014) Due to the increasing cost of soybean meal and concerns of excess N being excreted into the environment, new protein supplements have been developed. Two products that have shown potential in increasing N utilization efficiency are slow-release urea (SRU; Opt... |
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Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Bioorg. Med. Chem. Lett. 20 , 141-4, (2010) CTP synthase (CTPS) catalyzes the conversion of UTP to CTP and is a recognized target for the development of anticancer, antiviral, and antiprotozoal agents. Xanthine and related compounds inhibit CTPS activity (IC(50)=0.16-0.58mM). The presence of an 8-oxo f... |
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Nanoparticulate silver increases uric acid and allantoin excretion in rats, as identified by metabolomics.
J. Appl. Toxicol. 32(11) , 929-33, (2012) Metabolomic investigation of rat urine was employed to identify mammalian metabolites affected by ionic or nanoparticulate silver. Female and male Wistar rats were administered silver nanoparticles (2.25, 4.5 or 9.0 mg kg(-1) body weight per day) or ionic sil... |