Bupivacaine Hydrochloride

Bupivacaine Hydrochloride Structure
Bupivacaine Hydrochloride structure
Common Name Bupivacaine Hydrochloride
CAS Number 73360-54-0 Molecular Weight 342.90
Density N/A Boiling Point N/A
Molecular Formula C18H31ClN2O2 Melting Point 255-259℃
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

Differential requirement for IL-2 and IL-15 during bifurcated development of thymic regulatory T cells.

J. Immunol. 193(11) , 5525-33, (2014)

The developmental pathways of regulatory T cells (T(reg)) generation in the thymus are not fully understood. In this study, we reconstituted thymic development of Zap70-deficient thymocytes with a tetracycline-inducible Zap70 transgene to allow temporal disse...

The distinct effects of lipid emulsions used for "lipid resuscitation" on gating and bupivacaine-induced inhibition of the cardiac sodium channel Nav1.5.

Anesth. Analg. 117(5) , 1101-8, (2013)

Systemic administration of lipid emulsions is an established treatment for local anesthetic intoxication. However, it is unclear by which mechanisms lipids achieve this function. The high cardiac toxicity of the lipophilic local anesthetic bupivacaine probabl...

MK-801-induced behavioural sensitisation alters dopamine release and turnover in rat prefrontal cortex.

Psychopharmacol. Ser. 232(3) , 509-17, (2015)

Repeated exposure to psychostimulants that either increase dopamine (DA) release or target N-methyl-D-aspartate (NMDA) receptors can induce behavioural sensitisation, a phenomenon that may be important for the processes of addiction and even psychosis. A crit...

Serratus plane block - is a high volume of local anaesthetic needed?

Anaesthesia 69(2) , 192-3, (2014)

Implant of polymer containing pentacyclic triterpenes from Eugenia punicifolia inhibits inflammation and activates skeletal muscle remodeling.

Arch. Immunol. Ther. Exp. (Warsz.) 62(6) , 483-91, (2014)

Sustained chronic inflammation induces activation of genes involved in cellular proliferation and apoptosis, thereby causing skeletal muscle degeneration. To investigate in vitro effects of isolated pentacyclic triterpenes from Eugenia punicifolia (Ep-CM) upo...

Levobupivacaine for low-dose spinal anaesthesia.

Br. J. Anaesth. 112(2) , 380, (2014)

Accidental spinal potassium chloride injection successfully treated with spinal lavage.

Anaesthesia 69(1) , 72-6, (2014)

We describe the management of a 62-year-old man who developed severe pain, cramps, paraplegia and pulmonary oedema after the accidental administration of potassium chloride into the subarachnoid space. In addition to supportive treatment, we performed cerebro...

Arthroscopic capsular release for idiopathic frozen shoulder with intra-articular injection and a controlled manipulation.

Ann. R. Coll. Surg. Engl. 96(1) , 55-60, (2014)

The aim of this prospective study was to assess the immediate and long-term effectiveness of arthroscopic capsular release in a large cohort of patients with a precise and isolated diagnosis of stage II idiopathic frozen shoulder.All patients underwent a preo...

Binding of local anaesthetics to the lipid emulsion Clinoleic™ 20%.

Anaesth. Intensive Care 41(5) , 618-22, (2013)

Lipid emulsions have been used to treat cardiovascular collapse due to local anaesthetic toxicity. However, there are few data available on the comparative efficiency of the partitioning properties of available lipid emulsions in clinical use. This in vitro s...

The effect of lipid emulsion on intracellular bupivacaine as a mechanism of lipid resuscitation: an electrophysiological study using voltage-gated proton channels.

Anesth. Analg. 117(6) , 1293-301, (2013)

Lipid resuscitation has become a standard treatment for local anesthetic (LA) systemic toxicity, but its mechanisms remain to be fully elucidated. Although the partitioning effect is one of the proposed mechanisms, it is difficult to evaluate its impact indep...