Paraformaldehyde

Paraformaldehyde Structure
Paraformaldehyde structure
Common Name Paraformaldehyde
CAS Number 30525-89-4 Molecular Weight 62.068
Density 0.9±0.1 g/cm3 Boiling Point 82.5±8.0 °C at 760 mmHg
Molecular Formula C2H6O2 Melting Point 120-170ºC
MSDS Chinese USA Flash Point 39.9±6.3 °C
Symbol GHS02 GHS05 GHS07 GHS08
GHS02, GHS05, GHS07, GHS08
Signal Word Danger

RESOLFT nanoscopy with photoswitchable organic fluorophores.

Sci. Rep. 5 , 17804, (2015)

Far-field optical nanoscopy has been widely used to image small objects with sub-diffraction-limit spatial resolution. Particularly, reversible saturable optical fluorescence transition (RESOLFT) nanoscopy with photoswitchable fluorescent proteins is a powerf...

An optimized method to process mouse CNS to simultaneously analyze neural cells and leukocytes by flow cytometry.

J. Neurosci. Methods 247 , 23-31, (2015)

Flow cytometry is an efficient and powerful technique to characterize and quantify numerous cells. However, the strengths of this technique have not been widely harnessed in neurosciences due to the critical step of CNS tissue preparation into a single cell s...

Rapid titration of measles and other viruses: optimization with determination of replication cycle length.

PLoS ONE 6 , e24135, (2011)

Measles virus (MV) is a member of the Paramyxoviridae family and an important human pathogen causing strong immunosuppression in affected individuals and a considerable number of deaths worldwide. Currently, measles is a re-emerging disease in developed count...

Human dendritic cells infected with an adenoviral vector suppress proliferation of autologous and allogeneic T cells.

Immunology 125(4) , 469-79, (2008)

Dendritic cells (DCs) play a key role in the type and course of an immune response. The manipulation of human DCs to produce therapeutic agents by transduction with viral vectors is a growing area of research. We present an investigation into the effects of a...

Formation, Accumulation, and Hydrolysis of Endogenous and Exogenous Formaldehyde-Induced DNA Damage.

Toxicol. Sci. 146 , 170-82, (2015)

Formaldehyde is not only a widely used chemical with well-known carcinogenicity but is also a normal metabolite of living cells. It thus poses unique challenges for understanding risks associated with exposure. N(2-)hydroxymethyl-dG (N(2)-HOMe-dG) is the main...

Three puncture sites used for in utero electroporation show no significantly different negative impacts during gene transfer into the embryonic mouse brain.

Neurosci. Lett. 578 , 176-81, (2014)

Although various ways to manipulate genes in vivo exist, in utero electroporation is a widely used technique, especially in the field of neural development due to its many advantages. In this study, we focused on direct comparison between three puncture sites...

Human stefin B role in cell's response to misfolded proteins and autophagy.

PLoS ONE 9(7) , e102500, (2014)

Alternative functions, apart from cathepsins inhibition, are being discovered for stefin B. Here, we investigate its role in vesicular trafficking and autophagy. Astrocytes isolated from stefin B knock-out (KO) mice exhibited an increased level of protein agg...

Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis.

Autophagy 11 , 1130-45, (2015)

The glomerulus is a highly specialized capillary tuft, which under pressure filters large amounts of water and small solutes into the urinary space, while retaining albumin and large proteins. The glomerular filtration barrier (GFB) is a highly specialized fi...

A Structurally and Functionally Biomimetic Biphasic Scaffold for Intervertebral Disc Tissue Engineering.

PLoS ONE 10(6) , e0131827, (2015)

Tissue engineering offers high hopes for the treatment of intervertebral disc (IVD) degeneration. Whereas scaffolds of the disc nucleus and annulus have been extensively studied, a truly biomimetic and mechanically functional biphasic scaffold using naturally...

Ionic components of electric current at rat corneal wounds.

PLoS ONE 6(2) , e17411, (2011)

Endogenous electric fields and currents occur naturally at wounds and are a strong signal guiding cell migration into the wound to promote healing. Many cells involved in wound healing respond to small physiological electric fields in vitro. It has long been ...