CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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RV0540000
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CHEMICAL NAME :
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Paraformaldehyde
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CAS REGISTRY NUMBER :
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30525-89-4
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LAST UPDATED :
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199806
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DATA ITEMS CITED :
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16
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WISWESSER LINE NOTATION :
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/*VH*/ X
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062)
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration into the eye
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) ** ACUTE TOXICITY DATA **
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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800 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1070 mg/m3/4H
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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10000 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Skin and Appendages - corrosive (after topical exposure) Nutritional and Gross Metabolic - body temperature decrease
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REFERENCE :
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BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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9 gm/kg/90D-C
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TOXIC EFFECTS :
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Behavioral - fluid intake Nutritional and Gross Metabolic - weight loss or decreased weight gain
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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365 mL/kg/2Y-C
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TOXIC EFFECTS :
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Gastrointestinal - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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9 gm/kg/90D-C
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TOXIC EFFECTS :
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Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
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TYPE OF TEST :
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Morphological transformation
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TEST SYSTEM :
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Rodent - rat Embryo
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DOSE/DURATION :
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2200 ng/plate
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REFERENCE :
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JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 1,190,1981 *** REVIEWS *** TOXICOLOGY REVIEW 27ZTAP "Clinical Toxicology of Commercial Products--Acute Poisoning," 3rd ed., Gleason, M.N., et al., eds., Baltimore, Williams and Wilkins, 1969 Volume(issue)/page/year: 3,108,1969 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1528 No. of Facilities: 236 (estimated) No. of Industries: 5 No. of Occupations: 19 No. of Employees: 1872 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1528 No. of Facilities: 8271 (estimated) No. of Industries: 54 No. of Occupations: 65 No. of Employees: 146532 (estimated) No. of Female Employees: 20414 (estimated)
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