Androstenedione
Androstenedione structure
|
Common Name | Androstenedione | ||
|---|---|---|---|---|
| CAS Number | 63-05-8 | Molecular Weight | 286.409 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 431.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H26O2 | Melting Point | 170-173ºC | |
| MSDS | N/A | Flash Point | 161.1±25.7 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
|
Analysis of anabolic androgenic steroids in urine by full-capillary sample injection combined with a sweeping CE stacking method.
Anal. Bioanal. Chem 405(6) , 1969-76, (2013) This study describes an on-line stacking CE approach by sweeping with whole capillary sample filling for analyzing five anabolic androgenic steroids in urine samples. The five anabolic steroids for detection were androstenedione, testosterone, epitestosterone... |
|
|
Androgen synthesis in the gonadotropin-suppressed human testes can be markedly suppressed by ketoconazole.
J. Clin. Endocrinol. Metab. 98(3) , 1198-206, (2013) The concentration of intratesticular testosterone (IT-T) required for human spermatogenesis is unknown because spermatogenesis can persist despite the markedly reduced IT-T concentrations observed with LH suppression. Methods to lower IT-T further are needed ... |
|
|
Metabolism of the polycyclic musk galaxolide and its interference with endogenous and xenobiotic metabolizing enzymes in the European sea bass (Dicentrarchus labrax).
Environ. Pollut. 174 , 214-21, (2013) This study investigates the metabolism and mode of action of galaxolide (HHCB) in the European sea bass -Dicentrarchus labrax- following a single intraperitoneal injection of 50 mg HHCB/kg body weight. In addition, a group of fish was injected with 50 mg/kg o... |
|
|
Effects of alcohol consumption on plasma and urinary hormone concentrations in premenopausal women.
J. Natl. Cancer Inst. 85(9) , 722-7, (1993) Most epidemiologic studies of the relationship between alcohol consumption and breast cancer risk over the past decade have shown that persons who consume a moderate amount of alcohol are at 40%-100% greater risk of breast cancer than those who do not consume... |
|
|
Quantitation of urinary nucleosides by high-performance liquid chromatography.
J. Chromatogr. A. 763(1-2) , 193-7, (1997) It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patients with malignant tumours and they have been proposed as tumour markers. Their measurement could provide ... |
|
|
Alteration of urinary profiles of endogenous steroids and polyunsaturated fatty acids in thyroid cancer.
Cancer Lett. 202(2) , 173-9, (2003) To explore the possible involvement of a relationship between steroids and polyunsaturated fatty acids (PUFAs) in thyroid cancer, we studied the concentration levels of 21 endogenous urinary androgens and glucocorticoids, and 6 urinary PUFAs in female patient... |
|
|
Polyamine concentrations in pancreatic tissue, serum, and urine of patients with pancreatic cancer.
Pancreas 5(2) , 119-27, (1990) We investigated the total, free, and acetylated polyamine concentrations in pancreatic tissue, serum, and urine of 20 patients with pancreatic cancer, 30 healthy volunteers, and 40 patients with nonmalignant, gastrointestinal diseases by reversed-phase liquid... |
|
|
Preoperative levels of plasma micronutrients are related to endometrial cancer risk.
Acta Obstet. Gynecol. Scand. 88(4) , 434-9, (2009) To examine the relation between the plasma concentration of antioxidant micronutrients and endometrial cancer risk in Korean women.Hospital-based case-control study.Seven tertiary medical institutes in Korea.Incidence of 28 endometrial cancer cases were ident... |
|
|
Rapid, simple enzymatic assay of free L-fucose in serum and urine, and its use as a marker for cancer, cirrhosis, and gastric ulcers.
Clin. Chem. 36(3) , 474-6, (1990) We devised a kit for use with automated analyzers, for assay of urinary free L-fucose by means of a newly isolated L-fucose dehydrogenase (EC 1.1.1.122), and we measured L-fucose in healthy subjects, cancer patients, and patients with other diseases. It takes... |
|
|
11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione
J. Steroid Biochem. Mol. Biol. 138 , 132-42, (2013) • Etomidate inhibited DOC, deoxycortisol, A4 and T conversion in H295R cells. • CYP11B1 11β-hydroxylates A4 and T; CYP11B2 11β-hydroxylates T. • 11βHSD1 converts 11KA4 and 11KT; 11βHSD2 converts 11OHA4 and 11OHT. • Steroid 5α-reductase types 1 and 2 convert 1... |