N-Acetyl-D-lactosamine
N-Acetyl-D-lactosamine structure
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Common Name | N-Acetyl-D-lactosamine | ||
|---|---|---|---|---|
| CAS Number | 32181-59-2 | Molecular Weight | 383.34800 | |
| Density | 1.64 g/cm3 | Boiling Point | 805.5ºC at 760 mmHg | |
| Molecular Formula | C14H25NO11 | Melting Point | 191-192ºC | |
| MSDS | Chinese USA | Flash Point | 441ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.
J. Pharmacol. Exp. Ther. 353 , 505-16, (2015) c-Jun N-terminal kinases (JNKs) participate in many physiologic and pathologic processes, including inflammatory diseases. We recently synthesized the sodium salt of IQ-1S (11H-indeno[1,2-b]quinoxalin-11-one oxime) and demonstrated that it is a high-affinity ... |
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BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.
J. Exp. Med. 212 , 883-92, (2015) B cell activating factor (BAFF) stimulation of the BAFF receptor (BAFF-R) is essential for the homeostatic survival of mature B cells. Earlier in vitro experiments with inhibitors that block MEK 1 and 2 suggested that activation of ERK 1 and 2 MAP kinases is ... |
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Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.
J. Virol. 89 , 6918-27, (2015) Human immunodeficiency virus (HIV) in humans and simian immunodeficiency virus (SIV) in macaques (MAC) lead to chronic inflammation and AIDS. Natural hosts, such as African green monkeys (AGM) and sooty mangabeys (SM), are protected against SIV-induced chroni... |
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Microfluidic plug steering using surface acoustic waves.
Lab Chip 15 , 3030-8, (2015) Digital microfluidic systems, in which isolated droplets are dispersed in a carrier medium, offer a method to study biological assays and chemical reactions highly efficiently. However, it's challenging to manipulate these droplets in closed microchannel devi... |
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Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.
J. Immunol. 194(8) , 3723-34, (2015) The paracaspase MALT1 plays an important role in immune receptor-driven signaling pathways leading to NF-κB activation. MALT1 promotes signaling by acting as a scaffold, recruiting downstream signaling proteins, as well as by proteolytic cleavage of multiple ... |
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Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity.
Nat. Commun. 6 , 7114, (2015) The presence of lymph node (LN)-like vasculature in tumours, characterized by expression of peripheral node addressin and chemokine CCL21, is correlated with T-cell infiltration and positive prognosis in breast cancer and melanoma patients. However, mechanism... |
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Up-regulation of interleukin-22 mediates liver fibrosis via activating hepatic stellate cells in patients with hepatitis C.
Clin. Immunol. 158 , 77-87, (2015) Interleukin-22 (IL-22) is known to play a critical role in liver immunity. However, the role of IL-22 in HCV-associated liver fibrosis is poorly understood. In this study, patients with HCV infection disclosed significant increases in peripheral numbers of IL... |
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Organ-wide 3D-imaging and topological analysis of the continuous microvascular network in a murine lymph node.
Sci. Rep. 5 , 16534, (2015) Understanding of the microvasculature has previously been limited by the lack of methods capable of capturing and modelling complete vascular networks. We used novel imaging and computational techniques to establish the topology of the entire blood vessel net... |
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Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche.
Cancer Discov. 5(2) , 168-81, (2015) Metastasis is the leading cause of cancer-associated deaths. Although dissemination of tumor cells likely occurs early in tumorigenesis, the constituents of the microenvironment play essential rate-limiting roles in determining whether these cells will form c... |
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Synthetic Long Peptide Influenza Vaccine Containing Conserved T and B Cell Epitopes Reduces Viral Load in Lungs of Mice and Ferrets.
PLoS ONE 10 , e0127969, (2015) Currently licensed influenza vaccines mainly induce antibodies against highly variable epitopes. Due to antigenic drift, protection is subtype or strain-specific and regular vaccine updates are required. In case of antigenic shifts, which have caused several ... |