Acenaphthoquinone
Acenaphthoquinone structure
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Common Name | Acenaphthoquinone | ||
|---|---|---|---|---|
| CAS Number | 82-86-0 | Molecular Weight | 182.175 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 362.5±9.0 °C at 760 mmHg | |
| Molecular Formula | C12H6O2 | Melting Point | 249-252 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 150.2±4.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Addition of phenylacetylene to a magnesium complex of monoiminoacenaphtheneone (dpp-mian).
Dalton Trans. 44 , 20532-41, (2015) In the presence of formic acid, acenaphthenequinone (AQ) reacts with one molar equivalent of 2,6-diisopropylaniline in toluene to give monoiminoacenaphtheneone (3, dpp-mian) in good yield. Reduction of compound 3 with an excess of magnesium in thf results in ... |
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Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1.
J. Med. Chem. 50 , 5727-34, (2007) Carboxylesterases (CE) are ubiquitous enzymes responsible for the detoxification of xenobiotics, including numerous clinically used drugs. Therefore, the selective inhibition of these proteins may prove useful in modulating drug half-life and bioavailability.... |
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CaCl(2) as a bifunctional reusable catalyst: diversity-oriented synthesis of 4H-pyran library under ultrasonic irradiation.
Mol. Divers. 16(4) , 669-83, (2012) CaCl(2) is applied as an efficient reusable and eco-friendly bifunctional catalyst for the one-pot three-component synthesis of 4H-pyrans under ultrasonic irradiation. A broad range of substrates including the aromatic and heteroaromatic aldehydes, indoline-2... |
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An environmental quinoid polycyclic aromatic hydrocarbon, acenaphthenequinone, modulates cyclooxygenase-2 expression through reactive oxygen species generation and nuclear factor kappa B activation in A549 cells.
Toxicol. Sci. 95(2) , 348-55, (2007) Diesel exhaust particles (DEPs) contain oxygen-containing polycyclic aromatic hydrocarbons (PAHs) called quinoid PAHs. Some quinoid PAHs generate free radicals as they undergo enzymatic and nonenzymatic redox cycling with their corresponding semiquinone radic... |
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Activation of 5-lipoxygenase and NF-kappa B in the action of acenaphthenequinone by modulation of oxidative stress.
Toxicol. Sci. 101(1) , 152-8, (2008) Quinoid polycyclic aromatic hydrocarbons are potent redox-active compounds that undergo enzymatic and nonenzymatic redox cycling with their semiquinone radical. We previously reported that acenaphthenequinone (AcQ) can damage human lung epithelial A549 cells ... |
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Mechanism of allergic cross-reactions--II. Cross-stimulation, by chemically unrelated ligands, of rat basophilic leukemia cells sensitized with an anti-DNP IgE antibody.
Mol. Immunol. 28(6) , 655-9, (1991) Serotonin release from rat basophilic leukemia (RBL) cells, sensitized with a DNP-binding monoclonal IgE, was stimulated with solid surface (polystyrene)-bound DNP-amino acids. The stimulatory potency of DNP-amino acids was dependent on the structure of amino... |