2-Chlorophenothiazine
2-Chlorophenothiazine structure
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Common Name | 2-Chlorophenothiazine | ||
|---|---|---|---|---|
| CAS Number | 92-39-7 | Molecular Weight | 233.717 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 395.7±31.0 °C at 760 mmHg | |
| Molecular Formula | C12H8ClNS | Melting Point | 195-200 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 193.1±24.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Reversing the Warburg effect as a treatment for glioblastoma.
J. Biol. Chem. 288(13) , 9153-64, (2013) Glioblastoma multiforme (GBM), like most cancers, possesses a unique bioenergetic state of aerobic glycolysis known as the Warburg effect. Here, we documented that methylene blue (MB) reverses the Warburg effect evidenced by the increasing of oxygen consumpti... |
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Broad specific enzyme-linked immunosorbent assay for determination of residual phenothiazine drugs in swine tissues.
Anal. Biochem. 454 , 7-13, (2014) In this study, a novel generic hapten of phenothiazine drugs was synthesized by derivatization of 2-chlorophenothiazine with sodium bromoacetate. Then the hapten was coupled to bovine serum albumin for production of the monoclonal antibody. Results showed tha... |
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N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
J. Med. Chem. 54 , 4247-63, (2011) A total of 53 N-benzoylated phenoxazines and phenothiazines, including their S-oxidized analogues, were synthesized and evaluated for antiproliferative activity, interaction with tubulin, and cell cycle effects. Potent inhibitors of multiple cancer cell lines... |
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Synthesis of new 2-chlorophenothiazinothiadiazol-2-oxoazetidines: antimicrobial and antiinflammatory agents. Srivastava SK, et al.
Indian J. Chem. B 39(6) , 464-67, (2000)
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Structures and dynamics of the lowest excited triplet states and cation radicals of phenothiazine and 2-chlorophenothiazine: transient resonance Raman and absorption study. Sarata G, et al.
J. Mol. Struct. 413 , 49-59, (1997)
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X-Ray Diffraction Studies on Molecular Semiconductors Based on Charge-Transfer Complexes of Substituted Phenothiazines with 2, 3-Dichloro-5, 6-dicyano-p-benzoquinone. Singh RA, et al.
Cryst. Res. Technol. 26(2) , 201-5, (1991)
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Phase transfer catalysis in N-alkylation of the pharmaceutical intermediates phenothiazine and 2-chlorophenothiazine. Gozlan I, et al.
J. Heterocycl. Chem. 21 , 613-614, (2009)
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Nickel Catalyzed Synthesis of N-aryl and N-heteroaryl Substituted Benzene Sulphonamides and their Biological Activity Evaluation. Ugwu David I, et al.
Med. Chem. 4 , 357-360, (2014)
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