Rifaximin
Rifaximin structure
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Common Name | Rifaximin | ||
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| CAS Number | 80621-81-4 | Molecular Weight | 785.878 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C43H51N3O11 | Melting Point | 200-205ºC(dec) | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Methane biogenesis during sodium azide-induced chemical hypoxia in rats.
Am. J. Physiol. Cell Physiol. 304(2) , C207-14, (2013) Previous studies demonstrated methane generation in aerobic cells. Our aims were to investigate the methanogenic features of sodium azide (NaN(3))-induced chemical hypoxia in the whole animal and to study the effects of l-α-glycerylphosphorylcholine (GPC) on ... |
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Effectiveness of different therapeutic strategies in preventing diverticulitis recurrence.
Eur. Rev. Med. Pharmacol. Sci. 17(3) , 342-8, (2013) Colonic diverticulitis shows a high recurrence rate.To assess the efficacy of three different therapeutic strategies in preventing diverticulitis recurrence.One hundred thirty patients suffering from Acute Uncomplicated Diverticulitis (AUD) (81 males, 49 fema... |
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Combination therapy for the treatment and prevention of hepatic encephalopathy.
Ann. Pharmacother. 46(11) , 1559-63, (2012) To evaluate the efficacy and safety of combination therapy for the treatment and prevention of hepatic encephalopathy (HE).A PubMed MEDLINE search was conducted (1947-June 2012) using the key terms lactulose, lactitol, nonabsorbable disaccharide, metronidazol... |
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Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning.
PLoS ONE 10 , e0135556, (2015) Neglected tropical diseases cause significant morbidity and mortality and are a source of poverty in endemic countries. Only a few drugs are available to treat diseases such as leishmaniasis, Chagas' disease, human African trypanosomiasis and malaria. Since d... |
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The effect of rifaximin on gut flora and Staphylococcus resistance.
Dig. Dis. Sci. 58(6) , 1676-82, (2013) Rifaximin is a non-absorbed antibiotic relative of rifampicin. The location of effect and staphylococcal resistance are two recent potential concerns with rifaximin. In this study we evaluate the location of effect of rifaximin as well as the development of s... |
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DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.
Nucleic Acids Res. 39 , D1035-41., (2011) DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, pharmacology, pharmacokinetics, metabolism and pharmaceutic... |
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The role of antimicrobials in Crohn's disease.
Expert Rev. Gastroenterol. Hepatol. 7(3) , 281-8, (2013) This review summarizes literature regarding the role of antimicrobials for induction and maintenance of Crohn's disease (CD) remission. PubMed was searched (1966 to October 2012) for controlled trials involving adults and written in English. Five of the 13 id... |
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One year intermittent rifaximin plus fibre supplementation vs. fibre supplementation alone to prevent diverticulitis recurrence: a proof-of-concept study.
Dig. Liver Dis. 45(2) , 104-9, (2013) Evidence supporting appropriate medical therapy to prevent recurrence of colonic diverticulitis is limited. Our goal was to evaluate the potential of rifaximin given periodically in addition to fibre for the prophylaxis of recurrences.We conducted a multicent... |
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Biologic properties and clinical uses of rifaximin.
Expert Opin. Pharmacother. 12(2) , 293-302, (2011) Rifaximin is increasingly being used to treat acute and chronic gastrointestinal infections and disorders. The drug exerts its beneficial effect through a variety of gut-selective mechanisms involving the host intestinal microbiota.Abstracts of all publicatio... |
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Rifaximin pharmacology and clinical implications.
Expert Opin. Drug Metab. Toxicol. 5(6) , 675-82, (2009) Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, with a low gastrointestinal absorption and a good antibacterial activity. The antibacterial action covers Gram-positive and Gram-negative organisms, both aerobes and anaerobes. Its antimic... |