4-Aminobenzamidine dihydrochloride
4-Aminobenzamidine dihydrochloride structure
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Common Name | 4-Aminobenzamidine dihydrochloride | ||
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| CAS Number | 2498-50-2 | Molecular Weight | 208.088 | |
| Density | 1.26g/cm3 | Boiling Point | 289.8ºC at 760 mmHg | |
| Molecular Formula | C7H11Cl2N3 | Melting Point | >300 °C(lit.) | |
| MSDS | USA | Flash Point | 129ºC | |
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Comparative study on the inhibition of plasmin and delta-plasmin via benzamidine derivatives.
Biochem. Biophys. Res. Commun. 457(3) , 358-62, (2015) The potent fibrinolytic enzyme, plasmin has numerous clinical applications for recannulizing vessels obstructed by thrombus. Despite its diminutive size, 91 kDa, success in the recombinant expression of this serine protease has been limited. For this reason, ... |
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p-Aminobenzamidine as a fluorescent probe for the active site of serine proteases.
J. Biol. Chem. 257 , 3014, (1982) p-Aminobenzamidine is weakly fluorescent in neutral aqueous buffer, with excitation and emission maxima at 293 and 376 nm, respectively. Binding to trypsin results in a blue shift of the emission peak to 362 nm, and 50-fold fluorescence enhancement, while bin... |
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Comparative studies on the inhibition of trypsin, plasmin, and thrombin by derivatives of benzylamine and benzamidine.
Eur. J. Biochem. 6 , 502, (1968)
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STUDIES ON THE ACTIVE CENTER OF TRYPSIN. THE BINDING OF AMIDINES AND GUANIDINES AS MODELS OF THE SUBSTRATE SIDE CHAIN.
J. Biol. Chem. 240 , 1579, (1965)
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Specific adsorption of serine proteases on coated silica beads substituted with amidine derivatives.
J. Chromatogr. A. 510 , 123, (1990) Amidine derivatives interact with serine proteases, the inhibition being due to interactions between amidine functions and the active sites of the enzymes. Five different types of amidine (substituted or unsubstituted) were coupled to coated silica beads, whi... |
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Syntheses and applications of water-soluble reactive polymers for purification and immobilization of biomolecules.
Biotechnol. Bioeng. 34 , 1186, (1989) Reactive polymers have been prepared by copolymeriz-ing N-isopropyl acrylamide (NIPAM) with N-acryloxy-succinimide (NASI) or glycidyl methacrylate (GMA). The amino groups of ligands could react with the residues of NASI or GMA and the polymers could be precip... |
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The development and application of a new affinity partitioning system for enzyme isolation and purification.
Enzyme Microb. Technol. 12 , 663, (1990) A reactive water-soluble polymer was synthesized by copolymerizing N-isopropylacrylamide and glycidyl acrylate. The reactive polymer could react with the amino groups of enzymes/proteins or other ligands to form an affinity polymer. As a model, the reactive p... |