2,4-D Butyl ester

2,4-D Butyl ester Structure
2,4-D Butyl ester structure
Common Name 2,4-D Butyl ester
CAS Number 94-80-4 Molecular Weight 277.144
Density 1.2±0.1 g/cm3 Boiling Point 343.9±27.0 °C at 760 mmHg
Molecular Formula C12H14Cl2O3 Melting Point 9ºC
MSDS Chinese USA Flash Point 132.0±22.7 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Biochemical alterations in skeletal muscle induced by 2,4-dichlorophenoxyacetic butyl ester during chick embryonic development.

Biochem. Pharmacol. 40(11) , 2433-40, (1990)

2,4-Dichlorophenoxyacetic butyl ester (2,4-D b.e.) (3.1 mg/egg) was applied on fertile hen eggs before starting the incubation. Chicks hatched from treated eggs showed motor dysfunctions, postural troubles and edematous muscles. The electromyography revealed ...

Formulation and food deprivation affects 2,4-D neurobehavioral toxicity in rats.

Neurotoxicol. Teratol. 9(5) , 363-7, (1987)

The herbicide 2,4-Dichlorophenoxyacetic acid (2,4-D) is a commonly used herbicide and one component of Agent Orange. The herbicide is commonly formulated as the butyl ester. The effects of a 50:50 mixture of n-butyl and iso-butyl esters of 2,4-D (2,4-D mixed ...

Neurobehavioral toxicity of 2,4-D-n-butyl ester (2,4-D ester): tolerance and lack of cross-tolerance.

Neurotoxicol. Teratol. 10(1) , 75-9, (1988)

Daily administration of 2,4-dichlorophenoxyacetic acid-n-butyl ester to rats (2,4-D ester, 150 mg/kg/day SC) initially produced depressions in photocell locomotor activity and increases in landing foot splay. Maximal tolerance developed to these effects follo...

Nucleic acid content and residue determination in tissues of chicks born from 2,4-dichlorophenoxyacetic butyl ester treated eggs.

Drug Chem. Toxicol. 10(3-4) , 339-55, (1987)

The effects of 2,4-dichlorophenoxyacetic butyl ester (2,4-D b.e.) on protein and nucleic acid contents of different tissues of chicks born from externally treated hen's eggs were studied. Residues of 2,4-D b.e. were also determined and quantified by gas liqui...

2,4-D-n-butyl ester (2,4-D ester) induced ataxia in rats: role for n-butanol formation.

Neurotoxicol. Teratol. 10(1) , 81-4, (1988)

Three formulations of 2,4-D were tested in rats for their ability to increase landing foot splay, a measure of ataxia. When administered for three to four consecutive days, 2,4-D-n-butyl ester (150 mg/kg/day SC) produced significant increases in landing foot ...

Chick brain hypomyelination produced by 2,4-dichlorophenoxyacetic butyl ester treatment.

Neurotoxicology 6(3) , 133-7, (1985)

Fertilized hens' eggs were externally treated with 2,4-dichlorophenoxyacetic (2,4-D) butyl ester (2.4 mg/egg) before starting incubation. The specific activity of 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNPase) was diminished in the whole brain of animal...

Effects of 2,4-dichlorophenoxyacetic acid butyl ester on chick liver.

Arch. Environ. Contam. Toxicol. 25(2) , 204-11, (1993)

Fertilized hen eggs were externally treated with 3.1 mg 2,4-dichlorophenoxyacetic acid butyl ester (2,4-D ester) before starting incubation. Liver lipid composition, (14C)2,4-dichlorophenoxyacetic acid (14C-2,4-D) subcellular distribution and covalent binding...

Esterase activities during chick embryonic development and its relationship with the metabolism of 2,4-dichlorophenoxyacetic acid butyl ester.

Bull. Environ. Contam. Toxicol. 49(4) , 520-6, (1992)

Penetration studies and residue determinations of 2,4-dichlorophenoxyacetic acid butyl ester in fertile hen eggs and chicks hatched from treated eggs.

Drug Chem. Toxicol. 12(2) , 137-46, (1989)

Fertilized hen eggs were topically applied with 2,4-Dichlorophenoxyacetic acid butyl ester (3.1 mg/egg) before starting incubation. During the incubation time 20% of the compound applied on eggs was lost by volatilization. At different incubation times (0, 1,...

Neurotoxicity of 2,4-dichlorophenoxyacetic butyl ester in chick embryos.

Neurochem. Res. 18(3) , 353-9, (1993)

Fertilized hens' eggs were externally treated, before starting incubation, with a single dose of 2,4-Dichlorophenoxyacetic butyl ester (2,4-D b.e., 3.1 mg/egg). Chicks at different developmental stages were examined, extending from 10 day embryos to one day a...