Sinomenine
Sinomenine structure
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Common Name | Sinomenine | ||
|---|---|---|---|---|
| CAS Number | 115-53-7 | Molecular Weight | 329.390 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 513.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H23NO4 | Melting Point | 180ºC | |
| MSDS | N/A | Flash Point | 264.4±30.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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[Research advances of mechanism of sinomenine in treating rheumatoid arthritis].
Zhong Xi Yi Jie He Xue Bao 7(8) , 775-8, (2009)
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[New study progress of sinomenine].
Zhongguo Zhong Yao Za Zhi 30(20) , 1573-6, (2005) To further understand sinomenine, this paper has introduced the abstract technology, assaying, pharmaceutical chemistry, pharmacological action, pharmacotoxicology, pharmacokinetics and clinical application of sinomenine based on the important and significant... |
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Immunosuppressive and anti-inflammatory activities of sinomenine.
Int. Immunopharmacol. 11(3) , 373-6, (2011) Sinomenine (SN), a pure compound extracted from the Sinomenium acutum plant, has been found to inhibit T- and B-lymphocyte activation, proliferation and function and to interfere with the differentiation, recruitment and function of several other cell types, ... |
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Sinomenine versus NSAIDs for the treatment of rheumatoid arthritis: a systematic review and meta-analysis.
Planta Med. 74(12) , 1423-9, (2008) Sinomenine (SIN), an alkaloid isolated from CAULIS SINOMENII, has been used in the treatment of rheumatoid arthritis (RA) clinically. This study aimed to systematically evaluate the efficacy and safety of SIN by a comparison between SIN and non-steroidal anti... |
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Sinomenine inhibits microglia activation and attenuates brain injury in intracerebral hemorrhage.
Mol. Immunol. 60(2) , 109-14, (2014) Intracerebral hemorrhage (ICH) causes morbidity and mortality and commonly follows the reperfusion after an ischemic event. Microglial activation mediated cytokine and protease secretion contributes to brain injury in ICH. Previous studies have shown that sin... |