Miconazole Nitrate
Miconazole Nitrate structure
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Common Name | Miconazole Nitrate | ||
|---|---|---|---|---|
| CAS Number | 22832-87-7 | Molecular Weight | 479.141 | |
| Density | 1.451g/cm3 | Boiling Point | 555.1ºC at 760 mmHg | |
| Molecular Formula | C18H15Cl4N3O4 | Melting Point | 170-185ºC | |
| MSDS | Chinese USA | Flash Point | 289.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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HPLC and chemometric methods for the simultaneous determination of miconazole nitrate and nystatin.
J. Chromatogr. Sci. 50(10) , 855-61, (2012) High-performance liquid chromatography (HPLC) and chemometric methods were applied to the simultaneous determination of the two nonsteroidal antifungal drugs, miconazole (MIC) and nystatin (NYS). The applied chemometric techniques are multivariate methods inc... |
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Peel bond strength of resilient liner modified by the addition of antimicrobial agents to denture base acrylic resin.
J. Appl. Oral Sci. 20(6) , 607-12, (2012) In order to prolong the clinical longevity of resilient denture relining materials and reduce plaque accumulation, incorporation of antimicrobial agents into these materials has been proposed. However, this addition may affect their properties. |
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Prophylactic oral/topical non-absorbed antifungal agents to prevent invasive fungal infection in very low birth weight infants.
Cochrane Database Syst. Rev. 3 , CD003478, (2013) Invasive fungal infection is an important cause of mortality and morbidity in very preterm or very low birth weight infants. Uncertainty exists about the effect of prophylactic oral/topical non-absorbed antifungals to reduce mucocutaneous colonisation and so ... |
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In vitro antifungal activity of two tissue conditioners combined with nystatin, miconazole and fluconazole against Candida albicans.
J. Contemp. Dent. Pract. 13(5) , 695-8, (2012) To determine and compare antifungal activity of two tissue conditioners combined with nystatin, miconazole and fluconazole against Candida albicans.Two tissue conditioners Viscogel and GC Soft combined with nystatin, miconazole and fluconazole were tested aga... |
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A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast.
PLoS ONE 7(11) , e49004, (2012) Currently, statins are the only drugs acting on the mammalian isoprenoid pathway. The mammalian genes in this pathway are not easily amenable to genetic manipulation. Thus, it is difficult to study the effects of the inhibition of various enzymes on the inter... |
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Formulation and drying of miconazole and itraconazole nanosuspensions.
Int. J. Pharm. 443(1-2) , 209-20, (2013) Miconazole and itraconazole possess adequate membrane permeability, but only slight water solubility, which limits their bioavailability and antifungal effect. To increase their dissolution rate, the compounds were nanoground by media milling to produce nanos... |
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Antimicrobial activity of ibuprofen: new perspectives on an "Old" non-antibiotic drug.
Eur. J. Pharm. Sci. 71 , 93-8, (2015) Pharmaceutical industry has been encountering antimicrobial activity of non-antibiotics during suitability tests carried out prior to routine pharmacopoeial microbiological purity analysis of finished dosage forms. These properties are usually ignored or perc... |
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NO-donating oximes relax corpora cavernosa through mechanisms other than those involved in arterial relaxation.
J. Sex. Med. 11(7) , 1664-74, (2014) Erectile dysfunction (ED), as well as many cardiovascular diseases, is associated with impaired nitric oxide (NO) bioavailability. Recently, oxime derivatives have emerged as vasodilators due to their NO-donating capacities. However, whether these oximes offe... |
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Multicenter, double-blind, parallel group study investigating the non-inferiority of efficacy and safety of a 2% miconazole nitrate shampoo in comparison with a 2% ketoconazole shampoo in the treatment of seborrhoeic dermatitis of the scalp.
J. Dermatolog. Treat. 25(3) , 226-31, (2014) This study investigated the non-inferiority of efficacy and tolerance of 2% miconazole nitrate shampoo in comparison with 2% ketoconazole shampoo in the treatment of scalp seborrheic dermatitis.A randomized, double-blind, comparative, parallel group, multicen... |
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[Generalized cutaneous candidiasis in newborn at term].
Biomedica. 32(2) , 170-3, (2012) Cutaneous candidiasis is a disease that affects children as well as adults. The presentation may be localized or systemic, and with multiple etiological agents. The most prevalent infecting species in children differs from that of the adult. |