CK548

CK548 Structure
CK548 structure
Common Name CK548
CAS Number 388604-55-5 Molecular Weight 384.67500
Density N/A Boiling Point N/A
Molecular Formula C15H11BrClNO2S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Tumor Suppressor NF2 Blocks Cellular Migration by Inhibiting Ectodomain Cleavage of CD44.

Mol. Cancer Res. 13 , 879-90, (2015)

Ectodomain cleavage (shedding) of transmembrane proteins by metalloproteases (MMP) generates numerous essential signaling molecules, but its regulation is not totally understood. CD44, a cleaved transmembrane glycoprotein, exerts both antiproliferative or tum...