2-KETOHEXANOIC ACID SODIUM SALT

2-KETOHEXANOIC ACID SODIUM SALT Structure
2-KETOHEXANOIC ACID SODIUM SALT structure
Common Name 2-KETOHEXANOIC ACID SODIUM SALT
CAS Number 13022-85-0 Molecular Weight 152.12400
Density N/A Boiling Point N/A
Molecular Formula C6H9NaO3 Melting Point 240ºC (dec.)(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Calcium uptake by bovine epididymal spermatozoa is regulated by the redox state of the mitochondrial pyridine nucleotides.

Biol. Reprod. 40(4) , 744-51, (1989)

Immature caput epididymal sperm accumulate calcium from exogenous sources at a rate 2- to 4-fold greater than mature caudal sperm. Calcium accumulation by these cells, however, is maximal in the presence of lactate as external substrate. This stimulation of c...

Inhibition studies on LDH isoenzyme purified from Uromastix testes.

J. Enzym. Inhib. 10(3) , 187-93, (1996)

An LDH isoenzyme was purified to homogeneity from uromastix testes and its inhibition spectrum towards known LDH isoenzyme inhibitors studied. Platinum compounds inhibited the enzyme in the forward reaction (pyruvate-->lactate) only, n-hexanediol and colchici...

Lactate dehydrogenase-C4 is involved in heparin- and NADH-dependent bovine sperm capacitation.

Andrologie 34(2) , 91-7, (2002)

Lactate dehydrogenase C4 isoenzyme (LDH-C4) is involved in the energy metabolism of spermatozoa. Sperm capacitation is considered part of an oxidative process; an NADH oxidase of plasma membrane could be responsible for superoxide anion generation which is re...

GC-MS profiling of urinary organic acids evaluated as a quantitative method.

Clin. Chem. 42(10) , 1609-15, (1996)

We assessed the quantitative performances of a classical method for profiling urinary organic acids: ethyl acetate extraction/oxime-trimethylsilyl derivatization/GC-MS. Twenty-seven acids were quantified on the basis of specific ions in both scan and selected...

The stimulus-secretion coupling of amino acid-induced insulin release. Synergistic effects of L-glutamine and 2-keto acids upon insulin secretion.

Biochim. Biophys. Acta 677(1) , 32-8, (1981)

[Inhibition of postoperative muscular proteolysis by sodium alpha-ketoisocaproate: does a dose-effect relation exist?].

Ann. Fr. Anesth. Reanim. 4(4) , 351-4, (1985)

The inhibitory effect of branched chain amino acids on muscle protein breakdown has been attributed to the ketoanalogue of leucine, alpha-ketoisocaproic acid. In an attempt to demonstrate a possible dose-response relationship for ketoleucine, the postoperativ...

Do branched chain keto amino acids regulate their own metabolism?

Hepatology 8(6) , 1716-8, (1988)

Signal transduction in islet hormone release: interaction of nitric oxide with basal and nutrient-induced hormone responses.

Cell. Signal. 10(9) , 645-51, (1998)

We examined the relation between the islet NO system and islet hormone secretion induced by either the non-glucose nutrient alpha-ketoisocaproic acid (KIC) or, in some experiments, glucose. KIC dose dependently stimulated insulin but inhibited glucagon secret...

Determination of free D-amino acids with a bacterial transaminase: their depletion leads to inhibition of bacterial growth.

Anal. Biochem. 218(1) , 204-9, (1994)

A general procedure is described to determine the common free D-amino acids except D-proline in mixtures that also contain L-amino acids. The system employs exogenous pure bacterial D-amino acid transaminase coupled with 2-oxohexanoate, which accepts the amin...

Signal function of metabolism of neutral amino acids and 2-keto acids for initiation of insulin secretion.

J. Biol. Chem. 257(12) , 6631-3, (1982)

2-Ketocaproate and 2-ketoisocaproate were equally potent insulin secretagogues. The insulin secretory potency of L-leucine was less than half of that of the keto acids and L-norleucine did not induce any insulin release by isolated islets and by the perfused ...