4-Amino-1-benzylpiperidine
4-Amino-1-benzylpiperidine structure
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Common Name | 4-Amino-1-benzylpiperidine | ||
|---|---|---|---|---|
| CAS Number | 50541-93-0 | Molecular Weight | 190.285 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 281.2±33.0 °C at 760 mmHg | |
| Molecular Formula | C12H18N2 | Melting Point | 90-93ºC | |
| MSDS | Chinese USA | Flash Point | 113.9±20.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Studies on the collision-induced dissociation of adipoR agonists after electrospray ionization and their implementation in sports drug testing.
J. Mass Spectrom. 50(2) , 407-17, (2015) AdipoR agonists are small, orally active molecules capable of mimicking the protein adiponectin, which represents an adipokine with antidiabetic and antiatherogenic effects. Two adiponectin receptors were reported in the literature referred to as adipoR1 and ... |
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N-Benzylpiperidine derivatives of 1,2,4-thiadiazolidinone as new acetylcholinesterase inhibitors.
Eur. J. Med. Chem. 35(10) , 913-22, (2000) A new family of 1,2,4-thiadiazolidinone derivatives containing the N-benzylpiperidine fragment has been synthesised. The acetylcholinesterase (AChE) inhibitory activity of all compounds was measured using Ellman's method and some of them turned out to be as p... |
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Synthesis of new glycyrrhetinic acid (GA) derivatives and their effects on tyrosinase activity.
Bioorg. Med. Chem. 11(24) , 5345-52, (2003) To synthesize glycyrrhetinic acid (GA) derivatives (3, 4, 5, 10, 13, 14, 15, and 16), we first removed the ketonic group in the C-11 position, and the carboxylic function at the C-30 position was kept intact, reduced to an alcohol, or transformed to an aldehy... |
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An improved synthesis of butyl 4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-1-piperidineacetate (AU-224).
Chem. Pharm. Bull. 49(6) , 788-90, (2001) A new and facile route for the synthesis of the novel gastrointestinal prokinetic butyl 4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-1-piperidineacetate (1b), which exhibited potent gastro- and colon-prokinetic activities by oral administration without signif... |
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Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer's Disease.
ChemMedChem 11 , 1284-95, (2016) We discovered a small series of hit compounds that show multitargeting activities against key targets in Alzheimer's disease (AD). The compounds were designed by combining the structural features of the anti-AD drug donepezil with clioquinol, which is able to... |