Trifluorothymine
Trifluorothymine structure
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Common Name | Trifluorothymine | ||
|---|---|---|---|---|
| CAS Number | 54-20-6 | Molecular Weight | 180.085 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 350ºC | |
| Molecular Formula | C5H3F3N2O2 | Melting Point | 245-246 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Molecular structure and effects of intermolecular hydrogen bonding on the vibrational spectrum of trifluorothymine, an antitumor and antiviral agent.
J. Mol. Model. 18(9) , 4453-64, (2012) In the present work, the experimental and the theoretical vibrational spectra of trifluorothymine were investigated. The FT-IR (400-4000 cm(-1)) and μ-Raman spectra (100-4000 cm(-1)) of trifluorothymine in the solid phase were recorded. The geometric paramete... |
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Quantitative 19F NMR study of trifluorothymidine metabolism in rat brain.
NMR Biomed. 12(6) , 373-80, (1999) Metabolism of trifluorothymidine (TFT) and its transport across the blood-brain barrier (BBB) has been measured quantitatively in rats by fluorine-19 nuclear magnetic resonance spectroscopy ((19)F NMR). It is demonstrated that TFT crosses the BBB in micromola... |
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Synthesis and in vitro activity of D- and L-enantiomers of 5-(trifluoromethyl)uracil nucleoside derivatives.
Nucleosides Nucleotides Nucleic Acids 20(4-7) , 1123-5, (2001) Recently, beta-L-nucleoside analogues have emerged as a new class of sugar modified nucleosides with potential antiviral and/or antitumoral activity. As a part of our ongoing research on this topic, we decided to synthesize 5-CF3-beta-L-dUrd (7), the hitherto... |