2-Methylcyclohexa-2,5-diene-1,4-dione
2-Methylcyclohexa-2,5-diene-1,4-dione structure
|
Common Name | 2-Methylcyclohexa-2,5-diene-1,4-dione | ||
|---|---|---|---|---|
| CAS Number | 553-97-9 | Molecular Weight | 122.121 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 186.6±15.0 °C at 760 mmHg | |
| Molecular Formula | C7H6O2 | Melting Point | 66-67 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 64.9±17.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.
J. Med. Chem. 51 , 1706-18, (2008) Indoleamine 2,3-dioxygenase (IDO) is emerging as an important new therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. While small molecule inhibitors of IDO exist, ther... |
|
|
A class of benzenoid chemicals suppresses apoptosis in C. elegans.
ChemBioChem. 7(12) , 2010-5, (2006) Benzene is a human carcinogen that might act through both genotoxic and nongenotoxic mechanisms to promote tumorigenesis. The genotoxic effects of benzene are well established, however, its potential nongenotoxic roles in carcinogenesis are poorly understood.... |
|
|
Oxidative DNA damage by minor metabolites of toluene may lead to carcinogenesis and reproductive dysfunction.
Biochem. Biophys. Res. Commun. 261(2) , 478-83, (1999) Recently, the concern that toluene might have carcinogenic and reproductive toxic potential has been raised. We investigated the ability of DNA damage by minor metabolites of toluene, methylhydroquinone, and methylbenzoquinone, using (32)P-5'-end-labeled DNA ... |
|
|
Isolation and characterizations of quinone analogue-resistant mutants of bo-type ubiquinol oxidase from Escherichia coli.
Biochemistry 37(37) , 12744-52, (1998) Cytochrome bo is a member of the heme-copper terminal oxidase superfamily and serves as a four-subunit ubiquinol oxidase in the aerobic respiratory chain of Escherichia coli. To probe the location and structural properties of the ubiquinol oxidation site, we ... |
|
|
Odoriferous Defensive stink gland transcriptome to identify novel genes necessary for quinone synthesis in the red flour beetle, Tribolium castaneum.
PLoS Genet. 9(7) , e1003596, (2013) Chemical defense is one of the most important traits, which endow insects the ability to conquer a most diverse set of ecological environments. Chemical secretions are used for defense against anything from vertebrate or invertebrate predators to prokaryotic ... |
|
|
[Paracatalytic interaction of pyruvate decarboxylase with quinones in the presence of an organic solvent. Formation of an active site which hinders proton transfer].
Ukr. Biokhim. Zh. 65(4) , 11-6, (1993) Inactivation kinetics of pyruvate decarboxylase under joint action of substrate and substituted quinones in aqueous solutions which contain 1.0-13.5 vol.% of methyl alcohol has been investigated. The observed inactivation rate constant of pyruvate decarboxyla... |
|
|
NADH oxidation by quinone electron acceptors.
Biochim. Biophys. Acta 767(1) , 108-12, (1984) The rate constants of NADH oxidation by quinones are increased with the oxidation potential increase: log kox (M-1 X s-1) = -0.25 + 12.2 E0(7) (V) for o-quinones and log kox (M-1 X s-1) = -3.06 + 13.5 E0(7) (V) for p-quinones (pH 7.0, 25 degrees C). It is ass... |
|
|
Human accidents involving Rhinocricus spp., a common millipede genus observed in urban areas of Brazil.
Clin. Toxicol. (Phila.) 49(3) , 187-90, (2011) The most important millipede species causing accidents in Brazil is Rhinocricus padbergi (order Spirobolida, family Rhinocricidae), a vegetarian scavenger distributed from Central to South America. Eleven clinical cases of dermal and oral accidental exposures... |
|
|
Fucoxanthin, tetraprenylated toluquinone and toluhydroquinone metabolites from Sargassum heterophyllum inhibit the in vitro growth of the malaria parasite Plasmodium falciparum.
Z. Naturforsch., C, J. Biosci. 63(11-12) , 848-52, (2008) In the course of our search for antimalarial leads from marine algae, four metabolites, sargaquinoic acid, sargahydroquinoic acid, sargaquinal and fucoxanthin, were isolated from the South African alga Sargassum heterophyllum. Fucoxanthin and sargaquinal show... |
|
|
Anointing chemicals and ectoparasites: effects of benzoquinones from millipedes on the lone star tick, Amblyomma americanum.
J. Chem. Ecol. 31(1) , 63-75, (2005) Many mammals and birds roll on or rub themselves with millipedes that discharge benzoquinones. Chemicals transferred from millipedes onto the integument of anointing animals are thought to deter ectoparasites. We tested the lone star tick, Amblyomma americanu... |