![]() Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one structure
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Common Name | Indeno[1,2-b]furazano[3,4-E]pyrazin-9-one | ||
---|---|---|---|---|
CAS Number | 67200-34-4 | Molecular Weight | 224.175 | |
Density | 1.7±0.1 g/cm3 | Boiling Point | 437.2±55.0 °C at 760 mmHg | |
Molecular Formula | C11H4N4O2 | Melting Point | 296 °C(dec.) | |
MSDS | Chinese USA | Flash Point | 218.2±31.5 °C | |
Symbol |
![]() GHS07 |
Signal Word | Warning |
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase.
Nat. Biotechnol. 28 , 738 - 742, (2010) The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyperactivation of the mammalian TOR (mTOR) pathway in human cancers, strategies to enhance TOR pathway inhibition are needed. We used a yeast-based screen to... |
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