![]() H-D-Abu-OH structure
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Common Name | H-D-Abu-OH | ||
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CAS Number | 2623-91-8 | Molecular Weight | 103.120 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 215.2±23.0 °C at 760 mmHg | |
Molecular Formula | C4H9NO2 | Melting Point | 300ºC | |
MSDS | Chinese USA | Flash Point | 83.9±22.6 °C |
Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome.
Anal. Chem. 81(10) , 3919-32, (2009) We report a new quantitative metabolome profiling technique based on differential (12)C-/(13)C-isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and electrospray ionization Fourier-transform ion cyclotron resonance mass s... |
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Protein prosthesis: β-peptides as reverse-turn surrogates.
Protein Sci. 22(3) , 274-9, (2013) The introduction of non-natural modules could provide unprecedented control over folding/unfolding behavior, conformational stability, and biological function of proteins. Success requires the interrogation of candidate modules in natural contexts. Here, expr... |
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Correlation between symmetry breaker position and the preferences of conformationally constrained homopeptides: a molecular dynamics investigation.
Biopolymers 90(5) , 695-706, (2008) The conformational tendencies of C(alpha,alpha)-diethylglycine (Deg)-based peptides have been studied in solution using all atom molecular dynamics simulations. Specifically, the conformational effects of breaking the symmetry of the host Tfa-(Deg)(5)-OtBu (T... |
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Aminoacylation and translational quality control strategy employed by leucyl-tRNA synthetase from a human pathogen with genetic code ambiguity.
Nucleic Acids Res. 41(21) , 9825-38, (2013) Aminoacyl-tRNA synthetases should ensure high accuracy in tRNA aminoacylation. However, the absence of significant structural differences between amino acids always poses a direct challenge for some aminoacyl-tRNA synthetases, such as leucyl-tRNA synthetase (... |
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Continuous β-turn fold of an alternating alanyl/homoalanyl peptide nucleic acid.
Acta Crystallogr. D Biol. Crystallogr. 68(Pt 8) , 1067-70, (2012) The crystal structure of the PNA (peptide nucleic acid) oligomer H-Lys-HalG-AlaG-HalC-AlaG-HalC-AlaC-Lys-NH(2) (PNA1, amino acids with D-configuration are underlined, Ala = alanyl, Hal = homoalanyl) has been determined by ab initio direct methods and refined ... |
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Site-selective traceless Staudinger ligation for glycoprotein synthesis reveals scope and limitations.
ChemBioChem. 12(9) , 1383-6, (2011)
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Transaminase-catalyzed asymmetric synthesis of L-2-aminobutyric acid from achiral reactants.
Biotechnol. Lett. 31 , 1595-1599, (2009) Asymmetric synthesis of an unnatural amino acid was demonstrated by omega-transaminase from Vibrio fluvialis JS17. L-2-Aminobutyric acid was synthesized from 2-oxobutyric acid and benzylamine with an enantiomeric excess higher than 99%. The reaction showed se... |
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Removal of L-alanine from the production of L-2-aminobutyric acid by introduction of alanine racemase and D-amino acid oxidase.
Appl. Microbiol. Biotechnol. 90(3) , 903-10, (2011) L-2-Aminobutyric acid can be synthesized in a transamination reaction from L-threonine and L-aspartic acid as substrates by the action of threonine deaminase and aromatic aminotransferase, but the by-product L-alanine was produced simultaneously. A small amou... |
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One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders.
J. Cell. Mol. Med. 13(10) , 4229-38, (2009) Autism spectrum disorders (ASDs), which include the prototypic autistic disorder (AD), Asperger's syndrome (AS) and pervasive developmental disorders not otherwise specified (PDD-NOS), are complex neurodevelopmental conditions of unknown aetiology. The curren... |
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Crystal structure of the ω-aminotransferase from Paracoccus denitrificans and its phylogenetic relationship with other class III aminotransferases that have biotechnological potential.
Proteins 81(5) , 774-87, (2013) Apart from their crucial role in metabolism, pyridoxal 5'-phosphate (PLP)-dependent aminotransferases (ATs) constitute a class of enzymes with increasing application in industrial biotechnology. To provide better insight into the structure-function relationsh... |