1,2-Dimethylhydrazine dihydrochloride
1,2-Dimethylhydrazine dihydrochloride structure
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Common Name | 1,2-Dimethylhydrazine dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 306-37-6 | Molecular Weight | 133.02000 | |
| Density | 0.759 g/cm3 | Boiling Point | 81.5ºC at 760 mmHg | |
| Molecular Formula | C2H10Cl2N2 | Melting Point | 167-169 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
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Effect of buprenorphine on genotoxicity evaluation of chemicals by the rat liver micronucleus test with partial hepatectomy.
J. Toxicol. Sci. 40(1) , 109-14, (2015) In the view of animal welfare considerations, we investigated the suitability of modifying the rat liver micronucleus test with partial hepatectomy to include administration of an analgesic drug to minimize pain and distress as much as possible. The effects o... |
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Assessment of a twice dosing regimen both before and after partial hepatectomy in the rat liver micronucleus test
Mutat. Res. Genet. Toxicol. Environ. Mutagen. 782 , 18-23, (2015) • Effectiveness of twice dosing regimen was evaluated in the rat liver MN test. • Results from twice dosing regimen are similar to those from single dosing regimens. • Twice dosing regimen could detect clastogenic and aneugenic activity simultaneously. |
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Beta-endorphin cell therapy for cancer prevention.
Cancer Prev. Res. (Phila.) 8(1) , 56-67, (2015) β-Endorphin (BEP)-producing neuron in the hypothalamus plays a key role in bringing the stress axis to a state of homeostasis and maintaining body immune defense system. Long-term delivery of BEP to obtain beneficial effect on chemoprevention is challenging, ... |
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Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates the formation of aberrant crypt foci, mucin-depleted foci, and cell proliferation on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in Wistar rats.
Rejuvenation Res. 17(4) , 325-33, (2014) Aberrant crypt foci (ACF) and mucin-depleted foci (MDF) are pre-neoplastic lesions identified in the colon of carcinogen-treated rodents and in humans at high risk for colon cancer. The present study was carried out to divulge the protective potential of the ... |
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Chemopreventive action of non-steroidal anti-inflammatory drugs on the inflammatory pathways in colon cancer.
Biomed. Pharmacother. 78 , 239-47, (2016) Non-steroidal anti-inflammatory drugs (NSAIDs) are emerging as novel chemopreventive agents against a variety of cancers owing to their capability in blocking the tumor development by cellular proliferation and by promoting apoptosis. Inflammation is principa... |