2-Benzylpropionic acid

2-Benzylpropionic acid Structure
2-Benzylpropionic acid structure
Common Name 2-Benzylpropionic acid
CAS Number 1009-67-2 Molecular Weight 164.20100
Density 1.065 g/mL at 25ºC(lit.) Boiling Point 167-168ºC23 mm Hg(lit.)
Molecular Formula C10H12O2 Melting Point 39-41ºC(lit.)
MSDS Chinese USA Flash Point 113ºC
Symbol GHS07
GHS07
Signal Word Warning

Estimation of the number of enantioselective sites of bovine serum albumin using frontal chromatography.

Chirality 5(7) , 513-5, (1993)

On a column with bovine serum albumin (BSA) immobilized covalently to silica, the adsorption isotherms of the enantiomers of mandelic acid, tryptophan, 2-phenylbutyric acid, and N-benzoylalanine are measured using a buffered mobile phase. Knowing the amount o...

Induction of histone acetylation and growth regulation in eryrthroleukemia cells by 4-phenylbutyrate and structural analogs.

Anticancer Res. 19(3A) , 1971-6, (1999)

The objective of this investigation was to study the relationship between histone acetylation and growth inhibition by 4-phenylbutyrate and structural analogs. Inhibition of growth of DS19 mouse erythroleukemia cells and K562 human leukemic cells by 4-phenylb...

Chiral carboxylic acids and their effects on melting-point behaviour in co-crystals with isonicotinamide.

Acta Crystallogr. B 64(Pt 6) , 780-90, (2008)

The crystal structures of co-crystals of two systems of chiral carboxylic acids, optically active and racemic 2-phenylpropionic acid and 2-phenylbutyric acid, with isonicotinamide are reported to investigate the effects of the chirality of the chiral carboxyl...

Separation of enantiomers on HPLC chiral stationary phases based on human plasma alpha1-acid glycoprotein: effect of sugar moiety on chiral recognition ability.

Enantiomer 5(1) , 37-45, (2000)

HPLC chiral stationary phases based on human plasma alpha1-acid glycoprotein (AGP) and partially deglycosylated AGP (pd-AGP) were prepared to investigate the effects of sugar moiety of AGP on chiral discrimination of various solutes. Removal of a sugar moiety...

Enantioselective degradation and unidirectional chiral inversion of 2-phenylbutyric acid, an intermediate from linear alkylbenzene, by Xanthobacter flavus PA1.

J. Hazard. Mater. 192(3) , 1633-40, (2011)

Microbial degradation of the chiral 2-phenylbutyric acid (2-PBA), a metabolite of surfactant linear alkylbenzene sulfonates (LAS), was investigated using both racemic and enantiomer-pure compounds together with quantitative stereoselective analyses. A pure cu...

[Assay of 2-phenylbutyric acid in plasma with gas and liquid chromatography].

J. Chromatogr. A. 277 , 61-9, (1983)

Two chromatographic methods which allow the measurement of 2-phenylbutyric acid in serum are described: a gas chromatographic, after silylation, and a reversed-phase high-performance liquid chromatographic. The liquid chromatography with a fluorescent detecti...

Relative bioavailability of different butamirate citrate preparations after single dose oral administration to 18 healthy volunteers.

Int. J. Clin. Pharmacol. Ther. 35(3) , 117-22, (1997)

Eighteen volunteers have been treated with different oral formulations of butamirate citrate according to 2 randomized 2-way crossover designs. In the first study (study I) the test preparation was a syrup (Demotussol Hustensirup, Demopharm), and the referenc...

Cellular genomic reporter assays for screening and evaluation of inducers of fetal hemoglobin.

Hum. Mol. Genet. 13(2) , 223-33, (2004)

Reactivation of fetal hemoglobin (HbF) expression using pharmacological agents represents a potential strategy for the therapy of beta-thalassemia, sickle cell disease, HbE and other beta-hemoglobinopathies. However, the drugs currently available have low eff...

Iridium-catalyzed enantioselective hydrogenation of alpha,beta-unsaturated carboxylic acids.

J. Am. Chem. Soc. 130(27) , 8584-8585, (2008)

A highly efficient iridium-catalyzed hydrogenation of alpha,beta-unsaturated carboxylic acids has been developed by using chiral spiro-phosphino-oxazoline ligands, affording alpha-substituted chiral carboxylic acids in exceptionally high enantioselectivities ...

Development of a thickness shear mode acoustic sensor based on an electrosynthesized molecularly imprinted polymer using an underivatized amino acid as the template.

Analyst 126(2) , 189-94, (2001)

The preparation and characterization of electrosynthesized poly(o-phenylenediamine) (iPoPD) as a molecular imprinting material were studied by an in situ quartz crystal impedance method. The changes of delta f0, delta R1, delta L1 and delta C0 suggest that th...