Amorolfine hydrochloride
Amorolfine hydrochloride structure
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Common Name | Amorolfine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 78613-38-4 | Molecular Weight | 353.970 | |
| Density | 1.234 | Boiling Point | 78-82°C (9 Torr) | |
| Molecular Formula | C21H36ClNO | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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The low keratin affinity of efinaconazole contributes to its nail penetration and fungicidal activity in topical onychomycosis treatment.
Antimicrob. Agents Chemother. 58(7) , 3837-42, (2014) Onychomycosis is a common fungal nail disease that is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate. Keratin affinity of topical drugs is an important physicochemical property impacting therape... |
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Characterization of Antifungal Activity and Nail Penetration of ME1111, a New Antifungal Agent for Topical Treatment of Onychomycosis.
Antimicrob. Agents Chemother. 60 , 1035-9, (2016) Fungal nail infection (onychomycosis) is a prevalent disease in many areas of the world, with a high incidence approaching 23%. Available antifungals to treat the disease suffer from a number of disadvantages, necessitating the discovery of new efficacious an... |
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Mechanism of Action of ME1111, a Novel Antifungal Agent for Topical Treatment of Onychomycosis.
Antimicrob. Agents Chemother. 60 , 873-80, (2016) Despite the existing treatment options for onychomycosis, there remains a strong demand for potent topical medications. ME1111 is a novel antifungal agent that is active against dermatophytes, has an excellent ability to penetrate human nails, and is being de... |