Cytochalasin E
Cytochalasin E structure
|
Common Name | Cytochalasin E | ||
|---|---|---|---|---|
| CAS Number | 36011-19-5 | Molecular Weight | 495.564 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 705.1±60.0 °C at 760 mmHg | |
| Molecular Formula | C28H33NO7 | Melting Point | 206ºC | |
| MSDS | Chinese USA | Flash Point | 380.2±32.9 °C | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
|
Excessive expression of the plant kinesin TBK5 converts cortical and perinuclear microtubules into a radial array emanating from a single focus.
Plant Cell Physiol. 48(5) , 753-61, (2007) TBK5 is a plant-specific kinesin constantly expressed in tobacco BY-2 cells. An analysis of the distribution of green fluorescent protein-tagged TBK5 (GFP-TBK5) transiently expressed in BY-2 protoplasts revealed that TBK5 could associate with microtubules in ... |
|
|
Cytochalasin E alters the cytoskeleton and decreases ENaC activity in Xenopus 2F3 cells.
Am. J. Physiol. Renal Physiol. 307(1) , F86-95, (2014) Numerous reports have linked cytoskeleton-associated proteins with the regulation of epithelial Na(+) channel (ENaC) activity. The purpose of the present study was to determine the effect of actin cytoskeleton disruption by cytochalasin E on ENaC activity in ... |
|
|
Biosynthesis: A carbonate architect emerges.
Nat. Chem. Biol. 10(7) , 486-7, (2014)
|
|
|
A carbonate-forming Baeyer-Villiger monooxygenase.
Nat. Chem. Biol. 10(7) , 552-4, (2014) Despite the remarkable versatility displayed by flavin-dependent monooxygenases (FMOs) in natural product biosynthesis, one notably missing activity is the oxidative generation of carbonate functional groups. We describe a multifunctional Baeyer-Villiger mono... |
|
|
Effects of medium calcium, and agents affecting cytoskeletal function, on cellular volume and morphology in liver tissue in vitro.
J. Cell. Biochem. 113(6) , 1915-25, (2012) The possible role of an exocytotic, vesicular mechanism in cellular volume regulation under iso-osmotic conditions has been studied in slices of rat liver. The effects of incubation conditions and agents affecting the actin cytoskeleton were examined for chan... |
|
|
H2O2 plays different roles in determining penetration failure in three diverse plant-fungal interactions.
Plant J. 29(3) , 257-68, (2002) Fungal plant pathogens that attempt to penetrate and feed on living cells frequently trigger a localized plant defence response that results in fungal penetration failure. In the current study we demonstrate that breakdown products of the cell wall released b... |
|
|
Microtubule-dependent motility and orientation of the cortical endoplasmic reticulum in elongating characean internodal cells.
Cell Motil. Cytoskeleton 66(3) , 142-55, (2009) Motility of the endoplasmic reticulum (ER) is predominantly microtubule- dependent in animal cells but thought to be entirely actomyosin-dependent in plant cells. Using live cell imaging and transmission electron microscopy to examine ER motility and structur... |
|
|
Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1.
Metab. Eng. 13(6) , 723-32, (2011) Cytochalasins are a group of fungal secondary metabolites with diverse structures and bioactivities, including cytochalasin E produced by Aspergillus clavatus, which is a potent anti-angiogenic agent. Here, we report the identification and characterization of... |
|
|
Retinal pigment epithelial cells phagocytosis of T lymphocytes: possible implication in the immune privilege of the eye.
Br. J. Ophthalmol. 86(12) , 1417-21, (2002) To investigate the capability of retinal pigment epithelium (RPE) cells to phagocytose T lymphocytes and to further analyse the immunobiological consequences of this phagocytosis.Human RPE cells pretreated or not by cytochalasin, a phagocytosis inhibitor, wer... |
|
|
Actomyosin II contractility expels von Willebrand factor from Weibel-Palade bodies during exocytosis.
J. Cell Biol. 194(4) , 613-29, (2011) The study of actin in regulated exocytosis has a long history with many different results in numerous systems. A major limitation on identifying precise mechanisms has been the paucity of experimental systems in which actin function has been directly assessed... |