Ethisterone
Ethisterone structure
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Common Name | Ethisterone | ||
|---|---|---|---|---|
| CAS Number | 434-03-7 | Molecular Weight | 312.446 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 446.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C21H28O2 | Melting Point | 266-273ºC | |
| MSDS | Chinese USA | Flash Point | 190.2±21.3 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Evolutionary history and functional characterization of androgen receptor genes in jawed vertebrates.
Endocrinology 150 , 5415-27, (2009) Vertebrates show diverse sexual characters in sexually attractive and reproductive organs, which are regulated by steroid hormones, particularly androgens. However, the evolutionary history of androgen receptor (AR) gene remains largely unknown on the basis o... |
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An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
J. Med. Chem. 51 , 2047-56, (2008) A benchmark data set of steroids with known affinity for sex hormone-binding globulin (SHBG) has been widely used to validate popular molecular field-based QSAR techniques. We have expanded the data set by adding a number of nonsteroidal SHBG ligands identifi... |
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Extended use of transdermal norelgestromin/ethinyl estradiol: a randomized trial.
Obstet. Gynecol. 105(6) , 1389-96, (2005) To compare bleeding profiles and satisfaction among women using a norelgestromin/ethinyl estradiol (E2) transdermal contraceptive patch in an extended regimen to those among women using a traditional 28-day patch regimen.Healthy, regularly menstruating women ... |
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TOMOCOMD-CARDD descriptors-based virtual screening of tyrosinase inhibitors: evaluation of different classification model combinations using bond-based linear indices.
Bioorg. Med. Chem. 15 , 1483-503, (2007) A new set of bond-level molecular descriptors (bond-based linear indices) are used here in QSAR (quantitative structure-activity relationship) studies of tyrosinase inhibitors, for finding functions that discriminate between the tyrosinase inhibitor compounds... |
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Novel C,N-chelate platinum(II) antitumor complexes bearing a lipophilic ethisterone pendant.
J. Inorg. Biochem. 105(4) , 525-31, (2011) The novel steroidal carrier ligand 17-α-[4'-ethynyl-dimethylbenzylamine]-17-β-testosterone (ET-dmba 1) and the steroid--C,N-chelate platinum(II) derivatives [Pt(ET-dmba)Cl(L)] (L = DMSO (2) and PTA (3; PTA =1,3,5-triaza-7-phosphaadamantane)) have been prepare... |
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Effect of oral versus transdermal steroidal contraceptives on androgenic markers.
Am. J. Obstet. Gynecol. 192(6) , 2055-9, (2005) The purpose of this study was to compare biochemical androgen profiles in women treated with the contraceptive patch versus an oral contraceptive (OC).Twenty-four healthy women were randomly assigned to receive 3 cycles of either the contraceptive patch (ethi... |
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Vitellogenin induction by a mixture of steroidal estrogens in freshwater fishes and relevant risk assessment.
Environ. Toxicol. 24(5) , 484-91, (2009) The study method on combined effects of environmental contaminant mixture and ecological risk assessment was discussed. Batch tests were conducted to assess the in vivo potency of binary mixtures of estrogens using plasma vitellogenin concentrations in male c... |
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Cytotoxicity, cellular localisation and biomolecular interaction of non-covalent metallo-intercalators with appended sex hormone steroid vectors.
Dalton Trans. (48) , 10765-73, (2009) A range of terpyridine platinum(II) metallo-intercalators with bioactive steroids attached has been created with the aim of localizing cytotoxic drugs. Complexes where the steroid does not interfere with access to the terpyridine are shown to retain potent cy... |
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Steroids' transformations in Penicillium notatum culture.
Steroids 70(3) , 193-8, (2005) The application of Penicillium notatum genus for biotransformations of steroids has been investigated. The reactions observed include insertion of an oxygen atom into D-ring of steroids, 15alpha-hydroxylation of 17alpha-methyl testosterone derivatives, ester ... |
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Effects of nitric oxide on aldosterone synthesis and nitric oxide synthase activity in glomerulosa cells from bovine adrenal gland.
Endocrine 24(1) , 61-71, (2004) This study investigated the effects of two NO-releasing agents, diethylenetriamine-NO (deta-NO) and sodium nitroprusside (SNP), on basal, ACTH-, and angiotensin II (AngII)-stimulated aldosterone production in glomerulosa cells from bovine adrenal gland. NO do... |