9-Fluorenylmethyl chloroformate
9-Fluorenylmethyl chloroformate structure
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Common Name | 9-Fluorenylmethyl chloroformate | ||
|---|---|---|---|---|
| CAS Number | 28920-43-6 | Molecular Weight | 258.700 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 393.9±11.0 °C at 760 mmHg | |
| Molecular Formula | C15H11ClO2 | Melting Point | 62-64 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 143.6±11.4 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens.
J. Vet. Pharmacol. Ther. 37(4) , 406-12, (2014) Butyrate, a commonly applied feed additive in poultry nutrition, can modify the expression of certain genes, including those encoding cytochrome P450 (CYP) enzymes. In comparative in vitro and in vivo experiments, the effect of butyrate on hepatic CYP genes w... |
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Analysis of amino acids by HPLC/electrospray negative ion tandem mass spectrometry using 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl) derivatization.
Amino Acids 46(12) , 2799-808, (2014) A new method for the determination of amino acids is presented. It combines established methods for the derivatization of primary and secondary amino groups with 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl) with the subsequent amino acid specific detection o... |
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Development and validation of a high-performance liquid chromatography-fluorescence detection method for the accurate quantification of colistin in human plasma.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 980 , 48-54, (2015) Recently, colistin has become one of the most important drugs for treating infections caused by multidrug-resistant Gram-negative bacteria. Therapeutic drug monitoring is recommended to ensure the safety and efficacy of colistin and to improve clinical outcom... |
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Short-term transport of glyphosate with erosion in Chinese loess soil--a flume experiment.
Sci. Total Environ. 512-513 , 406-14, (2015) Repeated applications of glyphosate may contaminate the soil and water and threaten their quality both within the environmental system and beyond it through water erosion related processes and leaching. In this study, we focused on the transport of glyphosate... |
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Molecularly imprinted polymer dedicated to the extraction of glyphosate in natural waters.
J. Chromatogr. A. 1361 , 1-8, (2014) Three molecularly imprinted polymers (MIPs) have been synthesized in order to bind efficiently glyphosate (GLY) in natural waters (mineral and underground). Since the target analyte is polar and hydrophilic, electrostatic interactions and hydrogen bonds have ... |
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Leaching of Glyphosate and Aminomethylphosphonic Acid through Silty Clay Soil Columns under Outdoor Conditions.
J. Environ. Qual. 44 , 1667-73, (2015) Glyphosate [-(phosphono-methyl)-glycine] is the main herbicide used in the Chianti vineyards. Considering the pollution risk of the water table and that the vineyard tile drain may deliver this pollutant into nearby streams, the objective of the present study... |
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Understanding the self-assembly of Fmoc-phenylalanine to hydrogel formation.
Soft Matter 11 , 5353-64, (2015) Hydrogels of low molecular weight molecules are important in biomedical applications. Multiple factors are responsible for hydrogel formation, but their role in governing self-assembly to hydrogel formation is poorly understood. Herein, we report the hydrogel... |
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Synthesis and characterization of a new Peptide prodrug of glucosamine with enhanced gut permeability.
PLoS ONE 10 , e0126786, (2015) The aim of this study was to synthesize a peptide prodrug of glucosamine (GlcN) with increased gut permeability through the gut peptide transporter 1 (PepT1). Glycine-Valine ester derivative of GlcN (GVG) was synthesised using solid phase synthesis followed b... |
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Gastrointestinal transfer: in vivo evaluation and implementation in in vitro and in silico predictive tools.
Eur. J. Pharm. Sci. 63 , 233-42, (2014) The purpose of this study was to explore the transfer of drug solutions from stomach to small intestine and its impact on intraluminal drug concentrations in humans. The collected intraluminal data were used as reference to evaluate simulations of gastrointes... |
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Distributed Drug Discovery, Part 3: using D(3) methodology to synthesize analogs of an anti-melanoma compound.
J. Comb. Chem. 11(1) , 34-43, (2009) For the successful implementation of Distributed Drug Discovery (D(3)) (outlined in the accompanying Perspective), students, in the course of their educational laboratories, must be able to reproducibly make new, high quality, molecules with potential for bio... |