Di-1,3-cyclopentadien-1-ylruthenium

Di-1,3-cyclopentadien-1-ylruthenium Structure
Di-1,3-cyclopentadien-1-ylruthenium structure
Common Name Di-1,3-cyclopentadien-1-ylruthenium
CAS Number 1287-13-4 Molecular Weight 231.256
Density N/A Boiling Point 41.5ºC at 760 mmHg
Molecular Formula C10H10Ru Melting Point 199-201 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior.

J. Med. Chem. 48 , 2814-21, (2005)

A series of ruthenocene derivatives, 1-[4-(O(CH(2))(n)()N(CH(3))(2))phenyl]-1-(4-hydroxyphenyl)-2-ruthenocenylbut-1-ene, with n = 2-5, based on the structure of the breast cancer drug tamoxifen has been prepared. These compounds were obtained, via a McMurry c...

Group 8 metallocenes as bulky functional groups in glucopyranosides.

Carbohydr. Res. 365 , 26-31, (2013)

The functionalization of methyl D-glucopyranosides at positions 4 and 6 with bulky moieties was carried out by using ferrocenyl and ruthenocenyl substituents. The synthesis succeeded by reaction of the methyl D-glucopyranosides with the corresponding metalloc...

Structural investigation of the interactions of biotinylruthenocene with avidin.

Chem. Biol. Interact. 204(1) , 6-12, (2013)

The crystal structure of avidin, a protein from hen egg white, was determined in the form of a complex with biotinylruthenocene. This biotin-derived organometallic ligand is a potential anticancer agent for targeted therapy based upon avidin-biotin technology...

Adrenal-affinity of ruthenocenyl-derivatives of biogenic amines

Int. J. Nucl. Med. Biol. 12(1) , 1-2, (1985)

[Organ distribution of ruthenocenyl biogenic amine derivatives--radiodiagnostic agents for the adrenals and ovaries?].

Strahlenther. Onkol. 162(1) , 51-6, (1986)

The organ distribution of 103Ru labelled ruthenocenyl derivatives of tyramine, histamine, benzylamine, phenylethylamine and homoveratrylamine were measured in rats. The derivatives of tyramine, histamine and benzylamine showed a high affinity for the adrenal ...

[Enzymatic hydroxylation of ruthenocene and osmocene by liver microsomes].

Z. Naturforsch., C, J. Biosci. 37(1-2) , 136-8, (1982)

In buffer solution (pH 7,4) ruthenocene and osmocene are far more stable than ferrocene. The metallocenes ruthenocene and osmocene are metabolized by microsomes of mouse liver in the presence of NADPH and O2. The Km-values are similar for both metallocenes, t...

Cytotoxicity of ruthenocene-containing β-diketones.

Anticancer Res. 32(7) , 2915-8, (2012)

Ferrocene-containing β-diketones and cisplatin, [(NH(3))(2)PtCl(2)], possess strong antineoplastic activity. No information is available regarding the anticancer activity of the corresponding ruthenocene complexes. This study examined the cytotoxicity of stab...

Results of ERBF and ERPF measurements in healthy dogs with two new radiopharmaceutical principles.

Contrib. Nephrol. 56 , 49-52, (1987)

[Separation of [Rh-103m]-rhodocene derivatives from the parent [103Ru]ruthenocene derivatives and their organ distribution].

Int. J. Rad. Appl. Instrum. A. 38(1) , 67-9, (1987)

The radioactive decay of [103Ru]ruthenocene derivatives leads to 103mRh labelled rhodocinium derivatives, which can be separated by the extraction of a lipophilic solution of the ruthenocen derivate with water. The separation factor 103mRh/103Ru reaches value...

[Biochemistry of amino acid derivatives of [103Ru] ruthenocene. Comparison with 131I hippuran].

Int. J. Rad. Appl. Instrum. A. 37(6) , 491-5, (1986)

The potential radiopharmaceuticals: ruthenocenoyl alanine, ruthenocenoyl methionine, 1'-methyl-ruthenocenoyl glycine and its esters were labelled with 103Ru starting from the analogous ferrocene compounds. In a series of tests in mice and rats these substance...